Dimethyl succinate

Modify Date: 2024-01-03 19:45:41

Dimethyl succinate structure	Common Name	Dimethyl succinate
	CAS Number	106-65-0	Molecular Weight	146.141
	Density	1.1±0.1 g/cm3	Boiling Point	195.3±0.0 °C at 760 mmHg
	Molecular Formula	C₆H₁₀O₄	Melting Point	16-19 °C(lit.)
	MSDS	Chinese USA	Flash Point	85.0±0.0 °C

Name	Dimethyl succinate
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	195.3±0.0 °C at 760 mmHg
Melting Point	16-19 °C(lit.)
Molecular Formula	C₆H₁₀O₄
Molecular Weight	146.141
Flash Point	85.0±0.0 °C
Exact Mass	146.057907
PSA	52.60000
LogP	0.20
Vapour Pressure	0.4±0.3 mmHg at 25°C
Index of Refraction	1.411
Stability	Stable. Combustible. Incompatible with oxidizing agents, acids, bases, reducing agents.
Water Solubility	8.5 g/L (20 ºC)

Dimethyl succinate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WM7675000

CHEMICAL NAME :: Succinic acid, dimethyl ester

CAS REGISTRY NUMBER :: 106-65-0

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H10-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 18,677,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 18,677,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6235 No. of Facilities: 1260 (estimated) No. of Industries: 8 No. of Occupations: 18 No. of Employees: 15417 (estimated) No. of Female Employees: 6678 (estimated)

Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi
Risk Phrases	R36
Safety Phrases	S26-S24/25
RIDADR	UN 1993
WGK Germany	1
RTECS	WM7675000
HS Code	29171990

Precursor 10
CAS#:23055-10-9 DIMETHYL MALEATE CAS#:762-42-5 Dimethyl but-2-... CAS#:67-56-1 Methanol CAS#:110-15-6 Succinic acid
CAS#:108-30-5 Succinic anhydride CAS#:1634-04-4 Methyl tert-but... CAS#:624-48-6 dimethyl maleate CAS#:54509-73-8 ethene
CAS#:201230-82-2 carbon monoxide CAS#:624-49-7 Dimethyl fumarate
DownStream 10
CAS#:1099378-22-9 Methyl 4-hydrox... CAS#:105544-78-3 4-methoxy-4-oxo... CAS#:4146-43-4 Succinohydrazide CAS#:773-14-8 OCTAFLUOROTETRA...
CAS#:354-34-7 Trifluoroacetyl... CAS#:422-61-7 Pentafluoroprop... CAS#:335-42-2 perfluorobutyry... CAS#:5653-88-3 2-(Phenylmethyl...
CAS#:3878-55-5 4-Methoxy-4-oxo... CAS#:108-30-5 Succinic anhydride

HS Code	2917190090
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition.

PLoS ONE 9(12) , e115144, (2014)

Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation. There is significant in...

Process model and economic analysis of itaconic acid production from dimethyl succinate and formaldehyde.

Bioresour. Technol. 97(2) , 342-7, (2006)

A complete process model and economic analysis has been developed for itaconic acid production via catalytic condensation of dimethyl succinate and formaldehyde. The process model is based on experime...

Effects of the methyl esters of pyruvate, succinate and glutamate on the secretory response to meglitinide analogues in rat pancreatic islets.

Pharmacol. Res. 33(3) , 191-4, (1996)

The insulinotropic action of the meglitinide analogues KAD-1229, A-4166 and repaglinide was examined in rat pancreatic islets deprived of exogenous nutrient or incubated in the presence of nutrient se...

Butanedioic acid dimethyl ester

EINECS 203-419-9

dimethyl butanedioate

Succinic Acid Dimethyl Ester

Methyl succinate

MFCD00008466