Tamsulosin hydrochloride structure
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Common Name | Tamsulosin hydrochloride | ||
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CAS Number | 106463-17-6 | Molecular Weight | 444.973 | |
Density | N/A | Boiling Point | 595.5ºC at 760 mmHg | |
Molecular Formula | C20H29ClN2O5S | Melting Point | 228-230ºC | |
MSDS | Chinese USA | Flash Point | 313.9ºC | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Tamsulosin hydrochlorideTamsulosin hydrochloride((R)-(-)-YM12617;LY253351) is a selective α1 receptor antagonist.Target: α1 receptorTamsulosin is a selective α1 receptor antagonist that has preferential selectivity for the α1A receptor in the prostate versus the α1B receptor in the blood vessels. Tamsulosin-treated patients had a 0.30-fold lower risk of developing acute urinary retention compared with control patients. None of the International Continence Society male questionnaire domain scores showed significant changes between the groups [1]. tamsulosin can be recommended for treating men after catheterization for AUR, and can reduce the likelihood of the need for re-catheterization [2]. |
Name | tamsulosin hydrochloride |
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Synonym | More Synonyms |
Description | Tamsulosin hydrochloride((R)-(-)-YM12617;LY253351) is a selective α1 receptor antagonist.Target: α1 receptorTamsulosin is a selective α1 receptor antagonist that has preferential selectivity for the α1A receptor in the prostate versus the α1B receptor in the blood vessels. Tamsulosin-treated patients had a 0.30-fold lower risk of developing acute urinary retention compared with control patients. None of the International Continence Society male questionnaire domain scores showed significant changes between the groups [1]. tamsulosin can be recommended for treating men after catheterization for AUR, and can reduce the likelihood of the need for re-catheterization [2]. |
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Related Catalog | |
References |
Boiling Point | 595.5ºC at 760 mmHg |
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Melting Point | 228-230ºC |
Molecular Formula | C20H29ClN2O5S |
Molecular Weight | 444.973 |
Flash Point | 313.9ºC |
Exact Mass | 444.148560 |
PSA | 108.26000 |
LogP | 4.51290 |
Vapour Pressure | 3.79E-14mmHg at 25°C |
Storage condition | Desiccate at RT |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302-H315-H319-H335 |
Precautionary Statements | P301 + P312 + P330-P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Phrases | 22-36/37/38 |
Safety Phrases | 26 |
RIDADR | NONH for all modes of transport |
~% Tamsulosin hydr... CAS#:106463-17-6 |
Literature: EP2172443 A1, ; Page/Page column 12 ; |
Precursor 1 | |
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DownStream 0 |
Inhibition of smooth muscle force generation by focal adhesion kinase inhibitors in the hyperplastic human prostate.
Am. J. Physiol. Renal Physiol. 307(7) , F823-32, (2014) Smooth muscle contraction may be critical for lower urinary tract symptoms (LUTS) in patients with benign prostate hyperplasia and requires stable anchorage of the cytoskeleton to the cell membrane. T... |
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Effects of alpha1-adrenoceptor antagonist (tamsulosin) on incident of ejaculation and semen quality in the goat.
Andrologia 47(3) , 354-9, (2015) Male temporary contraception is occasionally required in some animals. Alpha1-adrenoceptor antagonist (tamsulosin) can cause ejaculation disorder. Two sets of Latin square were applied to six male goa... |
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Pharmacokinetic interaction of finasteride with tamsulosin hydrochloride: an open-label, randomized, 3-period crossover study in healthy Chinese male volunteers.
Clin. Ther. 37(2) , 462-72, (2015) The primary aim of this study was to evaluate whether there was clinically significant pharmacokinetic (PK) interaction between finasteride and tamsulosin in healthy Chinese male subjects.This was an ... |
TAMSULOSINHCL |
TAMSOLUSIN HYDROCHLORIDE |
YM 12617-1 |
(R)-Tamsulosin |
(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide hydrochloride |
5-[(2R)-2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzolsulfonamidhydrochlorid |
Tamsulosin HCl |
Tamsulosin hydrochloride |
Yutanal |
YM-617 |
UNII:11SV1951MR |
5-[(R)-2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]]-2-methoxybenzenesulfonamide Hydrochloride |
(R)-TAMSULOSIN HCL |
5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride |
Yutana |
TAMSULOSINE HYDROCHLORIDE |
FLOMAX |
benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, monohydrochloride |
Benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, hydrochloride (1:1) |
TAMSULOSIN HYDROCHLORIDE , CERTIFIED REFERENCE MATERIAL |
Tamsulosin (hydrochloride) |
MFCD00922997 |
PRADIF |
(R)-TAMSULOSIN HYDROCHLORIDE,WHITE TO OFF-WHITE SOLID |
(R)-Tamsulosin Hydrochloride |
(R)-5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide monohydrochloride |
TAMSOLUSIN HCL |
5-[(2R)-2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide hydrochloride (1:1) |
(-)-(R)-5-[2-[[2-(o-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide monohydrochloride |
HARNAL |
OMNIC |
(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide hydrochloride ee |
5-[(2R)-2-{[2-(2-éthoxyphénoxy)éthyl]amino}propyl]-2-méthoxybenzènesulfonamide chlorhydrate |
Omic |