Angoline hydrochloride

Modify Date: 2025-08-22 11:45:35

Angoline hydrochloride Structure
Angoline hydrochloride structure
Common Name Angoline hydrochloride
CAS Number 1071676-04-4 Molecular Weight 415.87
Density N/A Boiling Point N/A
Molecular Formula C22H22ClNO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Angoline hydrochloride


Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].

 Names

Name Angoline hydrochloride

 Angoline hydrochloride Biological Activity

Description Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].
Related Catalog
Target

IC50: 11.56 μM (IL6/STAT3 signaling pathway)

References

[1]. Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91.

 Chemical & Physical Properties

Molecular Formula C22H22ClNO5
Molecular Weight 415.87

 Safety Information

Hazard Codes Xi
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