Ilexsaponin A
Modify Date: 2025-08-26 23:15:00
Ilexsaponin A structure
|
Common Name | Ilexsaponin A | ||
|---|---|---|---|---|
| CAS Number | 108524-93-2 | Molecular Weight | 664.823 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 788.1±60.0 °C at 760 mmHg | |
| Molecular Formula | C36H56O11 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 240.1±26.4 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of Ilexsaponin AIlexsaponin A, isolated from the root of Ilex pubescens, attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. Ilexsaponin A can reduce myocardial infarct size, lower the serum levels of LDH, AST and CK-MB, increase cellular viability and inhibit apoptosis in hypoxia/reoxygenation cardiomyocytes[1]. |
| Name | Ilexsaponin A |
|---|---|
| Synonym | More Synonyms |
| Description | Ilexsaponin A, isolated from the root of Ilex pubescens, attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. Ilexsaponin A can reduce myocardial infarct size, lower the serum levels of LDH, AST and CK-MB, increase cellular viability and inhibit apoptosis in hypoxia/reoxygenation cardiomyocytes[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Ilexsaponin A significantly reduces proapoptotic proteins including caspase-3, cleaved caspase-3 and bax and increases anti-apoptotic protein bcl-2 in hypoxia/reoxygenation cardiomyocytes. Ilexsaponin A treatment increases the expression levels of p-Akt in hypoxia/reoxygenation cellular model and myocardial ischemia/reperfusion animal model[1]. |
| In Vivo | Ilexsaponin A (10 or 40 mg/kg) reduce the myocardial infarct size in a dose dependent manner in male Sprague-Dawley rats weighing 280-320 g[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 788.1±60.0 °C at 760 mmHg |
| Molecular Formula | C36H56O11 |
| Molecular Weight | 664.823 |
| Flash Point | 240.1±26.4 °C |
| Exact Mass | 664.382263 |
| LogP | 5.11 |
| Vapour Pressure | 0.0±6.2 mmHg at 25°C |
| Index of Refraction | 1.611 |
| Storage condition | 2-8℃ |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |
| 1-O-[(3β,5ξ)-3,19,23-Trihydroxy-23,28-dioxours-12-en-28-yl]-β-D-glucopyranose |
| β-D-Glucopyranose, 1-O-[(3β,5ξ)-3,19,23-trihydroxy-23,28-dioxours-12-en-28-yl]- |
| Ilexsaponin A1 |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Ilexsaponin A
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- BioBioPha
- China
- Product Name: Ilexsaponin A
- Price: ￥900.0/5mg
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Xueping-Zheng
- Email: 1477035482@qq.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Ilexsaponin A
- Price: ￥1178.0/20mg
- Purity: 98.0%
- Delivery: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Ilexsaponin A1
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥1340/1 mg
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