Psammaplin A
Modify Date: 2024-01-12 15:21:06
Psammaplin A structure
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Common Name | Psammaplin A | ||
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| CAS Number | 110659-91-1 | Molecular Weight | 664.38700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H24Br2N4O6S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Psammaplin APsammaplin A, a marine metabolite, is a potent inhibitor of HDAC and DNA methyltransferases. Psammaplin A ia a highly potent and selective DAC1 inhibitor with an IC50 of 0.9 nM. Psammaplin A possess the antimicrobial effect on the Gram-positive bacteria and inhibits DNA synthesis and DNA gyrase activity. Antitumor Activity[1][2]. |
| Name | OT-Key 21539 |
|---|---|
| Synonym | More Synonyms |
| Description | Psammaplin A, a marine metabolite, is a potent inhibitor of HDAC and DNA methyltransferases. Psammaplin A ia a highly potent and selective DAC1 inhibitor with an IC50 of 0.9 nM. Psammaplin A possess the antimicrobial effect on the Gram-positive bacteria and inhibits DNA synthesis and DNA gyrase activity. Antitumor Activity[1][2]. |
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| Related Catalog | |
| Target |
IC50: 0.9 nM (DAC1)[1] |
| References |
[2]. Psammaplin A, a Natural Bromotyrosine Derivative From a Sponge, Possesses the |
| Molecular Formula | C22H24Br2N4O6S2 |
|---|---|
| Molecular Weight | 664.38700 |
| Exact Mass | 661.95000 |
| PSA | 214.44000 |
| LogP | 4.46400 |
| Hazard Codes | Xi |
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| 3-(3-Bromo-4-hydroxy-phenyl)-N-[2-(2-{3-(3-bromo-4-hydroxy-phenyl)-2-[(Z)-hydroxyimino]-propionylamino}-ethyldisulfanyl)-ethyl]-2-[(Z)-hydroxyimino]-propionamide |
| Li0061 |
| bisprasin |
| psammaplin A |