Coenzyme Q10-d6

Modify Date: 2024-01-15 15:22:08

Coenzyme Q10-d6 Structure
Coenzyme Q10-d6 structure
Common Name Coenzyme Q10-d6
CAS Number 110971-02-3 Molecular Weight 869.38
Density 1.0±0.1 g/cm3 Boiling Point 869.0±65.0 °C at 760 mmHg
Molecular Formula C59H84D6O4 Melting Point N/A
MSDS N/A Flash Point 324.6±34.3 °C

 Use of Coenzyme Q10-d6


Coenzyme Q10-d6 is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

 Names

Name Coenzyme Q10-d6
Synonym More Synonyms

 Coenzyme Q10-d6 Biological Activity

Description Coenzyme Q10-d6 is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Yang YK, et al. Coenzyme Q10 treatment of cardiovascular disorders of ageing including heart failure, hypertension and endothelial dysfunction. Clin Chim Acta. 2015 Oct 23;450:83-9.

[3]. Bhagavan HN, et al. Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res. 2006 May;40(5):445-53.

[4]. Matthews RT, et al. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8892-7.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 869.0±65.0 °C at 760 mmHg
Molecular Formula C59H84D6O4
Molecular Weight 869.38
Flash Point 324.6±34.3 °C
Exact Mass 868.721558
LogP 20.93
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.526

 Synonyms

2,5-Cyclohexadiene-1,4-dione, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-3-methyl-5,6-bis(methyl-d3-oxy)-
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-3-methyl-5,6-bis[(2H3)methyloxy]-1,4-benzoquinone
coenzyme q10-d6