Azido-PEG12-alcohol

Modify Date: 2024-01-09 22:47:21

Azido-PEG12-alcohol Structure
Azido-PEG12-alcohol structure
Common Name Azido-PEG12-alcohol
CAS Number 1111239-69-0 Molecular Weight 615.71
Density N/A Boiling Point N/A
Molecular Formula C26H53N3O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG12-alcohol


Azido-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG12-alcohol

 Azido-PEG12-alcohol Biological Activity

Description Azido-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1007.

 Chemical & Physical Properties

Molecular Formula C26H53N3O13
Molecular Weight 615.71