Azido-PEG12-propargyl

Modify Date: 2024-01-13 23:44:45

Azido-PEG12-propargyl Structure
Azido-PEG12-propargyl structure
Common Name Azido-PEG12-propargyl
CAS Number 2264091-72-5 Molecular Weight 609.71
Density N/A Boiling Point N/A
Molecular Formula C27H51N3O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG12-propargyl


Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG12-propargyl

 Azido-PEG12-propargyl Biological Activity

Description Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

 Chemical & Physical Properties

Molecular Formula C27H51N3O12
Molecular Weight 609.71
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