Azide-PEG12-alcohol

Modify Date: 2024-01-10 15:32:45

Azide-PEG12-alcohol Structure
Azide-PEG12-alcohol structure
Common Name Azide-PEG12-alcohol
CAS Number 1821464-55-4 Molecular Weight 571.66
Density N/A Boiling Point N/A
Molecular Formula C24H49N3O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azide-PEG12-alcohol


Azide-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azide-PEG12-alcohol

 Azide-PEG12-alcohol Biological Activity

Description Azide-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H49N3O12
Molecular Weight 571.66