Methyl linoleate

Modify Date: 2025-08-20 18:06:23

Methyl linoleate Structure
Methyl linoleate structure
Common Name Methyl linoleate
CAS Number 112-63-0 Molecular Weight 294.472
Density 0.9±0.1 g/cm3 Boiling Point 373.3±21.0 °C at 760 mmHg
Molecular Formula C19H34O2 Melting Point -35ºC(lit.)
MSDS Chinese USA Flash Point 96.9±20.4 °C
Symbol GHS02 GHS07 GHS08 GHS09
GHS02, GHS07, GHS08, GHS09
Signal Word Danger

 Use of Methyl linoleate


Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins[1].

 Names

Name methyl linoleate
Synonym More Synonyms

 Methyl linoleate Biological Activity

Description Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins[1].
Related Catalog
In Vitro Sageretia thea fruit extracts rich in Methyl linoleate downregulate melanogenesis via the Akt/GSK3β signaling pathway. The HFSF and Methyl linoleate inhibit β-catenin-mediated transcriptional activation of MITF through the Akt/GSK3β signaling pathway[1].
References

[1]. Ko GA, et al. Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway. Nutr Res Pract. 2018 Feb;12(1):3-12.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 373.3±21.0 °C at 760 mmHg
Melting Point -35ºC(lit.)
Molecular Formula C19H34O2
Molecular Weight 294.472
Flash Point 96.9±20.4 °C
Exact Mass 294.255890
PSA 26.30000
LogP 7.64
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.465
Storage condition 2-8°C

 Safety Information

Symbol GHS02 GHS07 GHS08 GHS09
GHS02, GHS07, GHS08, GHS09
Signal Word Danger
Hazard Statements H225-H304-H315-H336-H410
Precautionary Statements P210-P261-P273-P301 + P310-P331-P501
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes F,Xn,N
Risk Phrases R11
Safety Phrases 23-24/25-62-61-60-33-29-16-9
RIDADR UN 1206 3/PG 2
WGK Germany 1
HS Code 2916190090

 Synthetic Route

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

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 Methyl linoleateBioassay

View more

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
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 Synonyms

Linoleic acid, methyl ester (8CI)
9,12-Octadecadienoic acid (Z,Z)-, methyl ester
Methyl (9Z,12Z)-9,12-octadecadienoate
Methyl linoleate
9,12-Octadecadienoic acid (9Z,12Z)-, methyl ester
Linoleic acid methyl ester
Methyl (9Z,12Z)-octadeca-9,12-dienoate
Methyl octadecadienoate
Methyl lineoleate
Methyl (Z,Z)-9,12-octadecadienoate
Methyl 9-cis,12-cis-octadecadienoate
Methyl cis,cis-9,12-octadecadienoate
Methyl cis,cis-octadeca-9,12-dienoate
EINECS 203-993-0
MFCD00009534
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