Methyl linoleate

Modify Date: 2026-07-07 08:45:24

Methyl linoleate Structure
Methyl linoleate structure
Common Name Methyl linoleate
CAS Number 112-63-0 Molecular Weight 294.472
Density 0.9±0.1 g/cm3 Boiling Point 373.3±21.0 °C at 760 mmHg
Molecular Formula C19H34O2 Melting Point -35ºC(lit.)
MSDS Chinese USA Flash Point 96.9±20.4 °C
Symbol GHS02 GHS07 GHS08 GHS09
GHS02, GHS07, GHS08, GHS09
Signal Word Danger

 Use of Methyl linoleate


Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins[1].

Summary: Methyl linoleate, Chinese name: 亚油酸甲酯, CAS number: 112-63-0, molecular formula: C19H34O2, molecular weight: 294.472. It is a transparent pale to dark yellow liquid with a melting point of -35ºC and a boiling point of 373.3±21.0 °C, density of 0.9±0.1 g/cm3. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name methyl linoleate
Synonym More Synonyms

 Methyl linoleate Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins[1].
Related Catalog
In Vitro Sageretia thea fruit extracts rich in Methyl linoleate downregulate melanogenesis via the Akt/GSK3β signaling pathway. The HFSF and Methyl linoleate inhibit β-catenin-mediated transcriptional activation of MITF through the Akt/GSK3β signaling pathway[1].
References

[1]. Ko GA, et al. Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway. Nutr Res Pract. 2018 Feb;12(1):3-12.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 0.9±0.1 g/cm3
Boiling Point 373.3±21.0 °C at 760 mmHg
Melting Point -35ºC(lit.)
Molecular Formula C19H34O2
Molecular Weight 294.472
Flash Point 96.9±20.4 °C
Exact Mass 294.255890
PSA 26.30000
LogP 7.64
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.465
Storage condition 2-8°C

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS02 GHS07 GHS08 GHS09
GHS02, GHS07, GHS08, GHS09
Signal Word Danger
Hazard Statements H225-H304-H315-H336-H410
Precautionary Statements P210-P261-P273-P301 + P310-P331-P501
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes F,Xn,N
Risk Phrases R11
Safety Phrases 23-24/25-62-61-60-33-29-16-9
RIDADR UN 1206 3/PG 2
WGK Germany 1
HS Code 2916190090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Articles35

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Optimization of supercritical fluid consecutive extractions of fatty acids and polyphenols from Vitis vinifera grape wastes.

J. Food Sci. 80(1) , E101-7, (2015)

In this study, supercritical fluid extraction has been successfully applied to a sequential fractionation of fatty acids and polyphenols from wine wastes (2 different vitis vinifera grapes). To this a...

Ultrasound intensification suppresses the need of methanol excess during the biodiesel production with Lipozyme TL-IM.

Ultrason. Sonochem. 27 , 530-5, (2015)

The synthesis of biodiesel from sunflower oil and methanol based on transesterification using the immobilized lipase from Thermomyces lanuginosus (Lipozyme TL-IM) has been investigated under silent co...

Oxidative stability of n-3-enriched chicken patties under different package-atmosphere conditions.

Food Chem. 168 , 372-82, (2015)

The oxidation processes were studied in chicken patties, enriched with n-3 fatty acids, after 8days of storage at 4°C, under different aerobic conditions, and following heat treatment. Significant eff...

 Methyl linoleateBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Linoleic acid, methyl ester (8CI)
9,12-Octadecadienoic acid (Z,Z)-, methyl ester
Methyl (9Z,12Z)-9,12-octadecadienoate
Methyl linoleate
9,12-Octadecadienoic acid (9Z,12Z)-, methyl ester
Linoleic acid methyl ester
Methyl (9Z,12Z)-octadeca-9,12-dienoate
Methyl octadecadienoate
Methyl lineoleate
Methyl (Z,Z)-9,12-octadecadienoate
Methyl 9-cis,12-cis-octadecadienoate
Methyl cis,cis-9,12-octadecadienoate
Methyl cis,cis-octadeca-9,12-dienoate
EINECS 203-993-0
MFCD00009534

 Methyl linoleate | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the melting point of methyl linoleate?
A: Melting point of methyl linoleate is -35ºC(lit.).
Q: What is the polar surface area (PSA) of methyl linoleate?
A: Polar surface area (PSA) of methyl linoleate is 26.30000.
Q: What is the English name of methyl linoleate?
A: The English name of methyl linoleate is methyl linoleate.
Q: What is the LogP of methyl linoleate?
A: LogP of methyl linoleate is 7.64.
Q: What are the downstream products of methyl linoleate?
A: Related downstream products(CAS) of methyl linoleate: 33001-45-5;127592-95-4;18418-21-8;544-35-4;506-43-4;14606-78-1;553-90-2;627-93-0;1732-10-1;1119-40-0.
Q: What is the CAS number of methyl linoleate?
A: CAS number of methyl linoleate is 112-63-0.
Q: What are the uses of methyl linoleate?
A: Main uses of methyl linoleate: Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins[1].
Q: What is the boiling point of methyl linoleate?
A: Boiling point of methyl linoleate is 373.3±21.0 °C at 760 mmHg.
Q: What is the molecular formula of methyl linoleate?
A: Molecular formula of methyl linoleate is C19H34O2.
Q: What is the safety information for methyl linoleate?
A: Safety information for methyl linoleate: 23-24/25-62-61-60-33-29-16-9.

 Methyl linoleatefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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