JNJ-40411813
Modify Date: 2025-08-25 15:49:06
JNJ-40411813 structure
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Common Name | JNJ-40411813 | ||
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| CAS Number | 1127498-03-6 | Molecular Weight | 344.87800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H25ClN2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JNJ-40411813JNJ-40411813 is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.IC50 value: 147 nM(EC50)Target: mGlu2RJNJ-40411813 displayed an optimal interplay between potency, selectivity, favorable ADMET/PK and cardiovascular safety profile, and central EEG activity. JNJ-40411813 has been investigated in the clinic for schizophrenia and anxious depression disorders. |
| Name | 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2-one |
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| Synonym | More Synonyms |
| Description | JNJ-40411813 is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.IC50 value: 147 nM(EC50)Target: mGlu2RJNJ-40411813 displayed an optimal interplay between potency, selectivity, favorable ADMET/PK and cardiovascular safety profile, and central EEG activity. JNJ-40411813 has been investigated in the clinic for schizophrenia and anxious depression disorders. |
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| Related Catalog | |
| References |
| Molecular Formula | C20H25ClN2O |
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| Molecular Weight | 344.87800 |
| Exact Mass | 344.16600 |
| PSA | 25.24000 |
| LogP | 4.75080 |
| Storage condition | 2-8℃ |
| 1'-butyl-3'-chloro-4-phenyl-3,4,5,6-tetrahydro-2H,1'H-[1,4']bipyridinyl-2'-one |
| JNJ-40411813 |