1-Acetyl-2-phenylhydrazine

Modify Date: 2024-01-02 17:32:25

1-Acetyl-2-phenylhydrazine Structure
1-Acetyl-2-phenylhydrazine structure
Common Name 1-Acetyl-2-phenylhydrazine
CAS Number 114-83-0 Molecular Weight 150.17800
Density 1.143g/cm3 Boiling Point 214.1ºC at 760mmHg
Molecular Formula C8H10N2O Melting Point 128-131 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of 1-Acetyl-2-phenylhydrazine


N'-Phenylacetohydrazide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 1-Acetyl-2-phenylhydrazine
Synonym More Synonyms

 1-Acetyl-2-phenylhydrazine Biological Activity

Description N'-Phenylacetohydrazide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.143g/cm3
Boiling Point 214.1ºC at 760mmHg
Melting Point 128-131 °C(lit.)
Molecular Formula C8H10N2O
Molecular Weight 150.17800
Exact Mass 150.07900
PSA 41.13000
LogP 1.61350
Vapour Pressure 1E-06mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AJ2900000
CHEMICAL NAME :
Acetic acid, 2-phenylhydrazide
CAS REGISTRY NUMBER :
114-83-0
BEILSTEIN REFERENCE NO. :
0742880
LAST UPDATED :
199706
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C8-H10-N2-O
MOLECULAR WEIGHT :
150.20
WISWESSER LINE NOTATION :
1VMMR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
270 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
105 mg/kg/7D-I
TOXIC EFFECTS :
Blood - other changes Blood - changes in erythrocyte (RBC) count
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
112 mg/kg/4W-I
TOXIC EFFECTS :
Blood - methemoglobinemia-carboxyhemoglobin Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
28 mg/kg/7D-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Blood - methemoglobinemia-carboxyhemoglobin Blood - changes in erythrocyte (RBC) count
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
31 gm/kg/79W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Vascular - tumors Lungs, Thorax, or Respiration - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
333 ug/plate
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83705 No. of Facilities: 174 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1744 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83705 No. of Facilities: 613 (estimated) No. of Industries: 20 No. of Occupations: 19 No. of Employees: 15429 (estimated) No. of Female Employees: 4988 (estimated)

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H317-H319-H335
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38;R43
Safety Phrases S22-S26-S36-S24/25
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS AJ2900000
Packaging Group III
Hazard Class 6.1
HS Code 29280090

 Synthetic Route

 Customs

HS Code 29280090

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 Synonyms

EINECS 204-055-3
N'-phenylacetohydrazide
1-Acetyl-2-Phenylhydrazine
MFCD00008672
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