1-Phenylpropane-1,2-dione

Modify Date: 2024-01-02 01:29:40

1-Phenylpropane-1,2-dione Structure
1-Phenylpropane-1,2-dione structure
Common Name 1-Phenylpropane-1,2-dione
CAS Number 579-07-7 Molecular Weight 148.159
Density 1.1±0.1 g/cm3 Boiling Point 228.0±9.0 °C at 760 mmHg
Molecular Formula C9H8O2 Melting Point <20ºC
MSDS Chinese USA Flash Point 84.4±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 1-Phenylpropane-1,2-dione


1-Phenylpropane-1,2-dione, isolated from young Ephedra sinica Stapf (Ephedraceae), is biosynthetic precursors of the ephedrine alkaloids[1][2].

 Names

Name 1-phenyl-1,2-propanedione
Synonym More Synonyms

 1-Phenylpropane-1,2-dione Biological Activity

Description 1-Phenylpropane-1,2-dione, isolated from young Ephedra sinica Stapf (Ephedraceae), is biosynthetic precursors of the ephedrine alkaloids[1][2].
Related Catalog
In Vitro The main active principles of E. sinica are the unique and taxonomically restricted adrenergic agonists phenylpropylamino alkaloids, also known as the ephedrine alkaloids[1].
References

[1]. Raz Krizevski, et al. Composition and Stereochemistry of Ephedrine Alkaloids Accumulation in Ephedra Sinica Stapf. Phytochemistry. 2010 Jun;71(8-9):895-903.

[2]. Raz Krizevski, et al. Benzaldehyde Is a Precursor of Phenylpropylamino Alkaloids as Revealed by Targeted Metabolic Profiling and Comparative Biochemical Analyses in Ephedra Spp. Phytochemistry. 2012 Sep;81:71-9.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 228.0±9.0 °C at 760 mmHg
Melting Point <20ºC
Molecular Formula C9H8O2
Molecular Weight 148.159
Flash Point 84.4±0.0 °C
Exact Mass 148.052429
PSA 34.14000
LogP 0.82
Vapour Pressure 0.1±0.5 mmHg at 25°C
Index of Refraction 1.520

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
WGK Germany 3
HS Code 2914399090

 Synthetic Route

 Customs

HS Code 2914399090
Summary 2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles23

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Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

J. Med. Chem. 48 , 2906-15, (2005)

Carboxylesterases (CE) are ubiquitous enzymes responsible for the metabolism of xenobiotics. Because the structural and amino acid homology among esterases of different classes, the identification of ...

Influence of composition on rate of polymerization contraction of light-curing resin composites.

Acta Odontol. Scand. 60(3) , 146-50, (2002)

A slow contraction may result in reduced gap formation when a restorative resin polymerizes in a dental cavity. It was the aim in the present work to investigate the rate of contraction in relation to...

Inhibition of the reconstituted mitochondrial oxoglutarate carrier by arginine-specific reagents.

Arch. Biochem. Biophys. 331(1) , 48-54, (1996)

The effect of arginine-specific reagents on the function of the purified and reconstituted oxoglutarate carrier protein of the inner mitochondrial membrane has been investigated. The alpha-dicarbonyl ...

 Synonyms

1-phenylpropane-1,2-dione
MFCD00008755
EINECS 209-435-2
1-Phenyl-1,2-propanedione
1,2-Propanedione, 1-phenyl-
1-phenyl-1,2-propandione
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Price: ¥1960/10 mM * 1  mL in DMSO

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