CB-7921220

Modify Date: 2024-01-31 11:17:38

Use of CB-7921220

CB-7921220 is an adenylate cyclase inhibitor.

Name	CB7921220
Synonym	More Synonyms

Description	CB-7921220 is an adenylate cyclase inhibitor.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adenylate Cyclase Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease
In Vitro	CB-7921220 shows a degree of isoform selectivity for adenylate cyclase (AC) 1, but cannot distinguish between AC1 and AC6. CB-7921220 has a more consistent predicted binding position in the two virtual docking screens, and has a binding conformation similar to ATP and P-site inhibitors, which may explain its lack of selectivity between AC1 and AC6[1].
References	[1]. Brand CS, et al. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.

6-[2-(4-aminophenyl)vinyl]-2-pyridinecarboxylic acid

CB-7921220

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Price: $119/10mM*1mLinDMSO

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