Propargyl-PEG5-CH2CO2-NHS

Modify Date: 2024-01-12 10:17:19

Propargyl-PEG5-CH2CO2-NHS Structure
Propargyl-PEG5-CH2CO2-NHS structure
Common Name Propargyl-PEG5-CH2CO2-NHS
CAS Number 1161883-51-7 Molecular Weight 387.38
Density N/A Boiling Point N/A
Molecular Formula C17H25NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG5-CH2CO2-NHS


Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name Propargyl-PEG4-O-C1-NHS ester

 Propargyl-PEG5-CH2CO2-NHS Biological Activity

Description Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Kussrow A, et al. Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scatteringinterferometry. Anal Chem. 2009 Jun 15;81(12):4889-97.

 Chemical & Physical Properties

Molecular Formula C17H25NO9
Molecular Weight 387.38
Storage condition 2-8°C