Propargyl-PEG5-NHS ester

Modify Date: 2024-01-10 00:16:59

Propargyl-PEG5-NHS ester Structure
Propargyl-PEG5-NHS ester structure
Common Name Propargyl-PEG5-NHS ester
CAS Number 1393330-40-9 Molecular Weight 401.408
Density 1.2±0.1 g/cm3 Boiling Point 497.6±55.0 °C at 760 mmHg
Molecular Formula C18H27NO9 Melting Point N/A
MSDS N/A Flash Point 254.8±31.5 °C

 Use of Propargyl-PEG5-NHS ester


Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 1-(4,7,10,13,16-Pentaoxanonadec-18-ynoyloxy)-2,5-pyrrolidinedione
Synonym More Synonyms

 Propargyl-PEG5-NHS ester Biological Activity

Description Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Zhenjun Diwu, et al. Polyfluoreno[4,5-cde]oxepine Conjugates and Their Use in Methods of Analyte Detection. US20170275418A1.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 497.6±55.0 °C at 760 mmHg
Molecular Formula C18H27NO9
Molecular Weight 401.408
Flash Point 254.8±31.5 °C
Exact Mass 401.168579
LogP -2.68
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.502
Storage condition 2-8°C

 Synonyms

1-(4,7,10,13,16-Pentaoxanonadec-18-ynoyloxy)-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[(1-oxo-4,7,10,13,16-pentaoxanonadec-18-yn-1-yl)oxy]-
MFCD22574798
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