Propargyl-PEG4-CH2CO2-NHS

Modify Date: 2024-01-08 15:00:11

Propargyl-PEG4-CH2CO2-NHS Structure
Propargyl-PEG4-CH2CO2-NHS structure
Common Name Propargyl-PEG4-CH2CO2-NHS
CAS Number 2144777-76-2 Molecular Weight 343.329
Density 1.3±0.1 g/cm3 Boiling Point 451.3±55.0 °C at 760 mmHg
Molecular Formula C15H21NO8 Melting Point N/A
MSDS N/A Flash Point 226.7±31.5 °C

 Use of Propargyl-PEG4-CH2CO2-NHS


Propargyl-PEG4-CH2CO2-NHS is a PEG derivative containing a propargyl group and an NHS group. The hydrophilic PEG spacer increases solubility in aqueous media. This reagent has a terminal NHS ester and is an amine reactive reagent for derivatizing peptides, antibodies, amine coated surfaces etc. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-NHS ester Click Chemistry to yield a stable triazole linkage.

 Names

Name 1-(3,6,9,12-Tetraoxapentadec-14-ynoyloxy)-2,5-pyrrolidinedione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 451.3±55.0 °C at 760 mmHg
Molecular Formula C15H21NO8
Molecular Weight 343.329
Flash Point 226.7±31.5 °C
Exact Mass 343.126709
LogP -2.19
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.505

 Synonyms

1-(3,6,9,12-Tetraoxapentadec-14-ynoyloxy)-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[(1-oxo-3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy]-