STO-609 (acetate)

Modify Date: 2025-08-25 19:01:22

STO-609 (acetate) structure	Common Name	STO-609 (acetate)
	CAS Number	1173022-21-3	Molecular Weight	374.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₄N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of STO-609 (acetate)

STO-609 acetate is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 acetate inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.

Name	7H-Benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, 7-oxo-, acetate (1:1)
Synonym	More Synonyms

Description	STO-609 acetate is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 acetate inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> Neuronal Signaling >> CaMK Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Research Areas >> Metabolic Disease
References	[1]. Tokumitsu H, et al. STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase. J Biol Chem. 2002 May 3;277(18):15813-8. [2]. Kukimoto-Niino M, et al. Crystal structure of the Ca²⁺/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609. J Biol Chem. 2011 Jun 24;286(25):22570-9.

Description

Related Catalog

Signaling Pathways >> Epigenetics >> AMPK

Signaling Pathways >> Neuronal Signaling >> CaMK

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> PI3K/Akt/mTOR >> AMPK

Research Areas >> Metabolic Disease

References

[1]. Tokumitsu H, et al. STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase. J Biol Chem. 2002 May 3;277(18):15813-8.

[2]. Kukimoto-Niino M, et al. Crystal structure of the Ca²⁺/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609. J Biol Chem. 2011 Jun 24;286(25):22570-9.

Molecular Formula	C₂₁H₁₄N₂O₅
Molecular Weight	374.35
Exact Mass	374.090271
PSA	108.97000
LogP	3.38100

7-Oxo-7H-benzimidazo[2,1-a]benzo[de]isoquinoline-3-carboxylic acid acetate (1:1)

7H-Benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, 7-oxo-, acetate (1:1)

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: STO-609 (acetate)
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: STO-609 (acetate)
Price: $500.0/100mg $1000.0/250mg $1900.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: STO-609 (acetate)
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: STO-609 (acetate)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.