BRACO 19 trihydrochloride
Modify Date: 2024-01-02 23:53:48
BRACO 19 trihydrochloride structure
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Common Name | BRACO 19 trihydrochloride | ||
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| CAS Number | 1177798-88-7 | Molecular Weight | 703.144 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H46Cl3N7O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of BRACO 19 trihydrochlorideBRACO-19 is a potent small molecule Telomerase inhibitor (IC50=115 nM) that inhibits expression of human telomerase reverse transcriptase (hTERT); induces cellular senescence and inhibits growth of uterine cancer cells in vitro, inhibits growth of uterine tumor xenografts in vivo. |
| Name | BRACO-19 |
|---|---|
| Synonym | More Synonyms |
| Description | BRACO-19 is a potent small molecule Telomerase inhibitor (IC50=115 nM) that inhibits expression of human telomerase reverse transcriptase (hTERT); induces cellular senescence and inhibits growth of uterine cancer cells in vitro, inhibits growth of uterine tumor xenografts in vivo. |
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| References | References 1. Gowan SM, et al. Mol Pharmacol. 2002 May;61(5):1154-62. 2. Burger AM, et al. Cancer Res. 2005 Feb 15;65(4):1489-96. 3. Incles CM, et al. Mol Pharmacol. 2003 Nov;64(5):1101-8. 4. Gunaratnam M, et al. Biochem Pharmacol. 2009 Jul 15;78(2):115-22. View Related Products by Target Telomerase |
| Molecular Formula | C35H46Cl3N7O2 |
|---|---|
| Molecular Weight | 703.144 |
| Exact Mass | 701.277832 |
| Hazard Codes | Xi |
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| N,N'-(9-{[4-(Dimethylamino)phenyl]amino}-3,6-acridinediyl)bis[3-(1-pyrrolidinyl)propanamide] trihydrochloride |
| 1-Pyrrolidinepropanamide, N,N'-[9-[[4-(dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-, hydrochloride (1:3) |
| BRACO-19 |
| N,N'-(9-(4-(Dimethylamino)phenylamino)acridine-3,6-diyl)bis(3-(pyrrolidin-1-yl)propanamide) hydrochloride |
| BRACO19 hydrochloride |
| MFCD23380200 |