Phenyl salicylate

Modify Date: 2025-08-21 10:40:48

Phenyl salicylate structure	Common Name	Phenyl salicylate
	CAS Number	118-55-8	Molecular Weight	214.217
	Density	1.3±0.1 g/cm3	Boiling Point	306.6±0.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₀O₃	Melting Point	41-43 °C(lit.)
	MSDS	Chinese USA	Flash Point	137.3±13.2 °C
	Symbol	GHS07	Signal Word	Warning

Name	phenyl salicylate
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	306.6±0.0 °C at 760 mmHg
Melting Point	41-43 °C(lit.)
Molecular Formula	C₁₃H₁₀O₃
Molecular Weight	214.217
Flash Point	137.3±13.2 °C
Exact Mass	214.062988
PSA	46.53000
LogP	3.55
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.615
Storage condition	room temp
Stability	Light sensitive. Incompatible with strong oxidants. Flammable.
Water Solubility	dioxane: 0.1 g/mL, clear, colorless

Phenyl salicylate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO6125000

CHEMICAL NAME :: Salicylic acid, phenyl ester

CAS REGISTRY NUMBER :: 118-55-8

BEILSTEIN REFERENCE NO. :: 0393969

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C13-H10-O3

MOLECULAR WEIGHT :: 214.23

WISWESSER LINE NOTATION :: QR BVOR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,837,1976

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,149,1954

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: RMSRA6 Revue Medicale de la Suisse Romande. (Societe Medicale de La Suisse Romande, 2 rue Bellefontaine, 1003 Lausanne, Switzerland) V.1- 1881- Volume(issue)/page/year: 15,561,1895 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 600 mg/kg

SEX/DURATION :: female 7-12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)

REFERENCE :: OCMJAJ Osaka City Medical Journal. (Osaka City Medical Center, 1-4-54, Asahi-machi, Abeno-ku, Osaka 545, Japan) V.1- 1954- Volume(issue)/page/year: 12,23,1966

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1200 mg/kg

SEX/DURATION :: female 7-9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: OCMJAJ Osaka City Medical Journal. (Osaka City Medical Center, 1-4-54, Asahi-machi, Abeno-ku, Osaka 545, Japan) V.1- 1954- Volume(issue)/page/year: 12,23,1966

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 600 mg/kg

SEX/DURATION :: female 7-9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: OCMJAJ Osaka City Medical Journal. (Osaka City Medical Center, 1-4-54, Asahi-machi, Abeno-ku, Osaka 545, Japan) V.1- 1954- Volume(issue)/page/year: 12,23,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80479 No. of Facilities: 241 (estimated) No. of Industries: 3 No. of Occupations: 8 No. of Employees: 2943 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80479 No. of Facilities: 471 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 5712 (estimated) No. of Female Employees: 2297 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	VO6125000
HS Code	2918230000

Precursor 9
CAS#:124-38-9 Carbon dioxide CAS#:108-95-2 Phenol CAS#:69-72-7 Salicylic acid CAS#:100-67-4 POTASSIUMPHENOLATE
CAS#:119-36-8 Methyl salicylate CAS#:201230-82-2 carbon monoxide CAS#:98-80-6 Phenylboronic acid CAS#:17954-26-6 1,2-dihydro-2-p...
CAS#:134-55-4 Benzoic acid,2-...
DownStream 10
CAS#:10586-70-6 Benzamide,N-dod... CAS#:36411-52-6 2-Hydroxy-N-1H-... CAS#:90-47-1 Xanthone CAS#:3722-51-8 3-hydroxy-9H-9-...
CAS#:719-41-5 1-Hydroxy-9H-xa... CAS#:20919-36-2 N-BENZYL-2-HYDR... CAS#:108-95-2 Phenol CAS#:101-84-8 Diphenyl oxide
CAS#:7120-45-8 2-phenoxy-benzo... CAS#:124-38-9 Carbon dioxide

HS Code	2918230000
Summary	2918230000 other esters of salicylic acid and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Leaching of additives and degradation products from cold-cured orthodontic resins.

Acta Odontol. Scand. 52(3) , 150-6, (1994)

Unstimulated saliva was collected from orthodontic patients and subjected to combined gas-chromatography and gas-chromatography/mass-spectrometry analyses. Saliva was collected before insertion of rem...

In vitro transformation of hamster embryo cells by 3-(N-salicyloyl)amino-1,2,4-triazole.

Toxicol. Lett. 7(3) , 211-5, (1981)

The in vitro carcinogenic activities of 3-(N-salicyloyl)amino-1,2,4-triazole (SAT) and its two components, 3-amino-1,2,4-triazole and phenyl salicylate were examined in a transformation assay with cry...

Fragrance material review on phenyl salicylate.

Food Chem. Toxicol. 45 Suppl 1 , S472-6, (2007)

A toxicologic and dermatologic review of phenyl salicylate when used as a fragrance ingredient is presented.

Phenyl-2-hydroxybenzoat

Salicylic acid phenyl ester

Seesorb 201

Benzoic acid, 2-hydroxy-, phenyl ester

Phenyl salicylate melting point

phenyl 2-hydroxybenzoate

Salicylic acid, phenyl ester

Seesorb K 201

salol

EINECS 204-259-2

MFCD00002213

2-hydroxybenzoic acid phenyl ester

Phenyl salicylate

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China
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China
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China
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China
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China
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China
Product Name: Phenyl salicylate
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Phenyl salicylate

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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Precursor & DownStream

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