ML-109
Modify Date: 2024-01-10 12:13:50
ML-109 structure
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Common Name | ML-109 | ||
|---|---|---|---|---|
| CAS Number | 1186649-91-1 | Molecular Weight | 523.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H29N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ML-109ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM. |
| Name | ML-109 |
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| Description | ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM. |
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| Related Catalog | |
| Target |
EC50: 40 nM (TSHR)[1]. |
| In Vitro | ML-109 (Compound 2) is a full agonist at TSHR with an EC50 of 40 nM and, like compound 1, it has no activity at FSHR or LHCGR. ML-109 contains an aminal, a functional group that is subject to hydrolysis and/or other degradation mechanisms. ML-109 is surprisingly stable at neutral and basic conditions (t1/2 of ~16 h) but is found to degrade at low pH (t1/2 of ~3 h)[1]. |
| References |
| Molecular Formula | C31H29N3O5 |
|---|---|
| Molecular Weight | 523.58 |
| Storage condition | 2-8℃ |