Hydroxy-PEG3-ethyl acetate

Modify Date: 2024-01-09 18:25:24

Hydroxy-PEG3-ethyl acetate Structure
Hydroxy-PEG3-ethyl acetate structure
Common Name Hydroxy-PEG3-ethyl acetate
CAS Number 118988-04-8 Molecular Weight 236.26200
Density N/A Boiling Point N/A
Molecular Formula C10H20O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG3-ethyl acetate


Hydroxy-PEG3-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name ethyl 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]acetate

 Hydroxy-PEG3-ethyl acetate Biological Activity

Description Hydroxy-PEG3-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H20O6
Molecular Weight 236.26200
Exact Mass 236.12600
PSA 74.22000