5-Nitrothiazol-2-amine

Modify Date: 2025-08-23 19:03:36

5-Nitrothiazol-2-amine structure	Common Name	5-Nitrothiazol-2-amine
	CAS Number	121-66-4	Molecular Weight	145.140
	Density	1.7±0.1 g/cm3	Boiling Point	345.1±15.0 °C at 760 mmHg
	Molecular Formula	C₃H₃N₃O₂S	Melting Point	195-200 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	162.5±20.4 °C
	Symbol	GHS07	Signal Word	Warning

Name	2-Amino-5-nitrothiazole
Synonym	More Synonyms

Density	1.7±0.1 g/cm3
Boiling Point	345.1±15.0 °C at 760 mmHg
Melting Point	195-200 °C (dec.)(lit.)
Molecular Formula	C₃H₃N₃O₂S
Molecular Weight	145.140
Flash Point	162.5±20.4 °C
Exact Mass	144.994598
PSA	112.97000
LogP	0.83
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.705
Stability	Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides.
Water Solubility	<0.1 g/100 mL at 20 ºC

5-Nitrothiazol-2-amine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ2800000

CHEMICAL NAME :: Thiazole, 2-amino-5-nitro-

CAS REGISTRY NUMBER :: 121-66-4

BEILSTEIN REFERENCE NO. :: 0126797

LAST UPDATED :: 199710

DATA ITEMS CITED :: 24

MOLECULAR FORMULA :: C3-H3-N3-O2-S

MOLECULAR WEIGHT :: 145.15

WISWESSER LINE NOTATION :: T5N CSJ BZ DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - leukemia Blood - lymphoma, including Hodgkin's disease

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 23 gm/kg/46W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - uterine tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 600 mg/kg

SEX/DURATION :: male 10 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 700 mg/kg

SEX/DURATION :: male 14 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - menstrual cycle changes or disorders

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 15600 ug/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),103,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 31,71,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 31,71,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R20/21/22;R40
Safety Phrases	S26-S45-S24/25
RIDADR	2811
WGK Germany	3
RTECS	XJ2800000
HS Code	2934100090

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HS Code	2934100090
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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Radiat. Res. 112(2) , 273-82, (1987)

Complexes of general formula [PtCl2(NH3)L] with one radiosensitizing ligand per platinum are compared with ligand L alone, complexes with two radiosensitizers per platinum [PtCl2L2], and their analogs...

2-amino-5-nitrothiazole.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 31 , 71-7, (1983)

2-Amino-5-nitrothiazole

2-Thiazolamine, 5-nitro-

5-nitro-2-thiazolylamin

5-Nitrothiazol-2-amine

5-Nitro-1,3-thiazol-2-amine

MFCD00005326

EINECS 204-490-9

2-AMINO-5-NITRO THIAZOLE

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China
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China
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China
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Amino-5-nitrothiazole
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Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 5-Nitrothiazol-2-amine
Price: ￥Inquiry/25kg
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5-Nitrothiazol-2-amine

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MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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