Protein Kinase C (19-31)

Modify Date: 2025-08-25 18:39:39

Protein Kinase C (19-31) Structure
Protein Kinase C (19-31) structure
Common Name Protein Kinase C (19-31)
CAS Number 121545-65-1 Molecular Weight 1543.82
Density N/A Boiling Point N/A
Molecular Formula C67H118N26O16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Protein Kinase C (19-31)


Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins[1][2].

 Names

Name protein kinase c (19-31)
Synonym More Synonyms

 Protein Kinase C (19-31) Biological Activity

Description Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins[1][2].
Related Catalog
References

[1]. Mellor H, et al. The extended protein kinase C superfamily. Biochem J. 1998 Jun 1;332 ( Pt 2):281-92.

[2]. Nishizuka Y (1995). Protein kinase C and lipid signaling for sustained cellular responses" (abstract). FASEB J. 9 (7): 484–96.

 Chemical & Physical Properties

Molecular Formula C67H118N26O16
Molecular Weight 1543.82
Exact Mass 1542.92000
PSA 736.44000
LogP 3.78570
InChIKey OLYXRRDLXDCSNP-UHFFFAOYSA-N
SMILES CC(C)CC(NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(N)=O)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)O)C(C)C

 Synonyms

rfarkgalrqknv
protein kinase c fragment 19-31 amide
arg-phe-ala-arg-lys-gly-ala-leu-arg-gln-lys-asn-val-nh2
pkc inhibitor peptide
protein kinase c inhibitor peptide 19-31
h-arg-phe-ala-arg-lys-gly-ala-leu-arg-gln-lys-asn-val-oh
arg-phe-ala-arg-lys-gly-ala-leu-arg-gln-lys-asn-val
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