NC-005
Modify Date: 2024-09-09 10:28:08
NC-005 structure
|
Common Name | NC-005 | ||
|---|---|---|---|---|
| CAS Number | 1237540-74-7 | Molecular Weight | 663.815 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C40H45N3O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NC-005A potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 44 nM, 105 and 225-fold selectivity over β2i and β1i subunit, respecitvely; shows cytotoxicity against multiple myeloma cells with IC50 of 30 nM-1.5 uM. |
| Name | NC-005 |
|---|
| Description | A potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 44 nM, 105 and 225-fold selectivity over β2i and β1i subunit, respecitvely; shows cytotoxicity against multiple myeloma cells with IC50 of 30 nM-1.5 uM. |
|---|---|
| References | References 1. Britton M, et al. Chem Biol. 2009 Dec 24;16(12):1278-89. 2. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209. View Related Products by Target Proteasome |
| Molecular Formula | C40H45N3O6 |
|---|---|
| Molecular Weight | 663.815 |