Ribociclib

Modify Date: 2025-08-26 05:23:59

Ribociclib Structure
Ribociclib structure
Common Name Ribociclib
CAS Number 1256963-02-6 Molecular Weight 440.972
Density 1.3±0.1 g/cm3 Boiling Point 679.3±65.0 °C at 760 mmHg
Molecular Formula C22H29ClN8 Melting Point N/A
MSDS N/A Flash Point 364.6±34.3 °C

 Use of Ribociclib


CDK4-IN-1 is a selective inhibitor of cyclin-dependent kinase 4.

 Names

Name 4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 679.3±65.0 °C at 760 mmHg
Molecular Formula C22H29ClN8
Molecular Weight 440.972
Flash Point 364.6±34.3 °C
Exact Mass 440.220367
PSA 85.86000
LogP 3.19
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.644
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Synonyms

2-Pyrimidinamine, 4-[3-chloro-5-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-
4-(5-chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine
4-(3-Chloro-5-isopropyl-1H-pyrazol-4-yl)-N-{5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl}-2-pyrimidinamine
2-Pyrimidinamine, 4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-
4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-{5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl}-2-pyrimidinamine
QC-9704
LEE011
Ribociclib
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