TC-E 5006

Modify Date: 2024-01-10 18:59:08

TC-E 5006 Structure
TC-E 5006 structure
 Common Name TC-E 5006
CAS Number 1257395-14-4 Molecular Weight 499.54000
Density N/A Boiling Point N/A
Molecular Formula C29H29F4NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TC-E 5006


(Rac)-BIIB042 (Compound 10) is an modulator of γ-Secretase. (Rac)-BIIB042 reduces Amyloid-β 42 level with an EC50 value of 0.39 µM. (Rac)-BIIB042 can be used for the study of Alzheimer's disease[1].

 Names

Name 2-(6-((4-fluorophenyl)(4-methylpiperidin-1-yl)methyl)-4'-(trifluoromethyl)biphenyl-3-yl)propanoic acid

 TC-E 5006 Biological Activity

Description (Rac)-BIIB042 (Compound 10) is an modulator of γ-Secretase. (Rac)-BIIB042 reduces Amyloid-β 42 level with an EC50 value of 0.39 µM. (Rac)-BIIB042 can be used for the study of Alzheimer's disease[1].
Related Catalog
References

[1]. Peng H, et al. Discovery of BIIB042, a Potent, Selective, and Orally Bioavailable γ-Secretase Modulator. ACS Med Chem Lett. 2011 Aug 5;2(10):786-91.  

 Chemical & Physical Properties

Molecular Formula C29H29F4NO2
Molecular Weight 499.54000
Exact Mass 499.21300
PSA 40.54000
LogP 7.45880
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Chemsrc provides TC-E 5006(CAS#:1257395-14-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TC-E 5006 are included as well.>> amp version: TC-E 5006

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