TC-E 5006

Modify Date: 2024-01-10 18:59:08

TC-E 5006 structure	Common Name	TC-E 5006
	CAS Number	1257395-14-4	Molecular Weight	499.54000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₉F₄NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TC-E 5006

(Rac)-BIIB042 (Compound 10) is an modulator of γ-Secretase. (Rac)-BIIB042 reduces Amyloid-β 42 level with an EC50 value of 0.39 µM. (Rac)-BIIB042 can be used for the study of Alzheimer's disease[1].

Name	2-(6-((4-fluorophenyl)(4-methylpiperidin-1-yl)methyl)-4'-(trifluoromethyl)biphenyl-3-yl)propanoic acid

Description	(Rac)-BIIB042 (Compound 10) is an modulator of γ-Secretase. (Rac)-BIIB042 reduces Amyloid-β 42 level with an EC50 value of 0.39 µM. (Rac)-BIIB042 can be used for the study of Alzheimer's disease[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Peng H, et al. Discovery of BIIB042, a Potent, Selective, and Orally Bioavailable γ-Secretase Modulator. ACS Med Chem Lett. 2011 Aug 5;2(10):786-91.

Molecular Formula	C₂₉H₂₉F₄NO₂
Molecular Weight	499.54000
Exact Mass	499.21300
PSA	40.54000
LogP	7.45880