endo-BCN-PEG2-NH2

Modify Date: 2024-01-06 11:51:58

endo-BCN-PEG2-NH2 structure	Common Name	endo-BCN-PEG2-NH2
	CAS Number	1263166-93-3	Molecular Weight	324.41500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₈N₂O₄	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of endo-BCN-PEG2-NH2

endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-[(1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
Synonym	More Synonyms

Description	endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₇H₂₈N₂O₄
Molecular Weight	324.41500
Exact Mass	324.20500
PSA	82.81000
LogP	2.23530
Storage condition	-20°C

RIDADR	NONH for all modes of transport

Readily accessible bicyclononynes for bioorthogonal labeling and three-dimensional imaging of living cells.

Angew. Chem. Int. Ed. Engl. 49 , 9422-9425, (2010)

MFCD19705418

DC Chemicals Limited
China
Product Name: endo-BCN-PEG2-NH2
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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