Sulfabenzamide

Modify Date: 2024-01-05 18:56:23

Sulfabenzamide Structure
Sulfabenzamide structure
Common Name Sulfabenzamide
CAS Number 127-71-9 Molecular Weight 276.311
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C13H12N2O3S Melting Point 180-184 °C
MSDS Chinese USA Flash Point N/A

 Use of Sulfabenzamide


Sulfabenzamide is a intermediate in the synthesis of organic and pharmaceutical.

 Names

Name Sulfabenzamide
Synonym More Synonyms

 Sulfabenzamide Biological Activity

Description Sulfabenzamide is a intermediate in the synthesis of organic and pharmaceutical.
Related Catalog

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Melting Point 180-184 °C
Molecular Formula C13H12N2O3S
Molecular Weight 276.311
Exact Mass 276.056854
PSA 97.64000
LogP 1.19
Index of Refraction 1.636
Storage condition 2-8°C
Water Solubility 0.3 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV5802500
CHEMICAL NAME :
Benzamide, N-sulfanilyl-
CAS REGISTRY NUMBER :
127-71-9
BEILSTEIN REFERENCE NO. :
2139003
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H12-N2-O3-S
MOLECULAR WEIGHT :
276.33
WISWESSER LINE NOTATION :
ZR DSWMVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03348

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes N
Safety Phrases S22-S24/25
RIDADR 3249
WGK Germany 3
RTECS CV5802500
Packaging Group III
Hazard Class 6.1(b)
HS Code 2934999090

 Synthetic Route

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles10

More Articles
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

J. Sci. Ind. Res. 65(10) , 808, (2006)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug Metab. Dispos. 38 , 2302-8, (2010)

Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predicti...

 Synonyms

Benzamide, N-[(4-aminophenyl)sulfonyl]-
N-[(4-Aminophenyl)sulfonyl]benzamide
N-(4-Aminobenzenesulfonyl)benzamide
4-Amino-N-benzoylbenzenesulfonamide
N-Benzoylsulfanilamide
Sulfabenzamide
N-(4-aminophenyl)sulfonylbenzamide
MFCD00044890
Sulfabenzamide(SB)
Sultrin
EINECS 204-859-4
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