Azeliragon HCl structure
|
Common Name | Azeliragon HCl | ||
---|---|---|---|---|
CAS Number | 1284150-65-7 | Molecular Weight | 605.038 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C32H40Cl3N3O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Azeliragon HClAzeliragon, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy. |
Name | 3-(4-{2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl}phenoxy)-N,N-diethyl-1-propanamine dihydrochloride |
---|---|
Synonym | More Synonyms |
Molecular Formula | C32H40Cl3N3O2 |
---|---|
Molecular Weight | 605.038 |
Exact Mass | 603.218628 |
1-Propanamine, 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]-N,N-diethyl-, hydrochloride (1:2) |
3-(4-{2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl}phenoxy)-N,N-diethyl-1-propanamine dihydrochloride |