TRC051384 HCl

Modify Date: 2024-02-25 20:38:36

TRC051384 HCl structure	Common Name	TRC051384 HCl
	CAS Number	1333327-56-2	Molecular Weight	502.01
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₂ClN₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TRC051384 HCl

TRC051384 hydrochloride is a potent inducer of heat shock protein 70 (HSP70). TRC051384 hydrochloride exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 hydrochloride can be used for the research of ischemic stroke[1][2].

Name	TRC051384
Synonym	More Synonyms

Description	TRC051384 hydrochloride is a potent inducer of heat shock protein 70 (HSP70). TRC051384 hydrochloride exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 hydrochloride can be used for the research of ischemic stroke[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP Research Areas >> Neurological Disease
References	[1]. Mohanan A, et, al. Delayed intervention in experimental stroke with TRC051384--a small molecule HSP70 inducer. Neuropharmacology. 2011 May;60(6):991-9. [2]. Chen T, et, al. HSP70 attenuates neuronal necroptosis through the HSP90α-RIPK3 pathway following neuronal trauma. Mol Biol Rep. 2023 Sep;50(9):7237-7244.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> HSP

Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

Research Areas >> Neurological Disease

References

[1]. Mohanan A, et, al. Delayed intervention in experimental stroke with TRC051384--a small molecule HSP70 inducer. Neuropharmacology. 2011 May;60(6):991-9.

[2]. Chen T, et, al. HSP70 attenuates neuronal necroptosis through the HSP90α-RIPK3 pathway following neuronal trauma. Mol Biol Rep. 2023 Sep;50(9):7237-7244.