Fenoterol-d6 hydrobromide

Modify Date: 2024-01-02 18:52:46

Fenoterol-d6 hydrobromide structure	Common Name	Fenoterol-d6 hydrobromide
	CAS Number	1286129-04-1	Molecular Weight	390.30200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₆BrD₆NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fenoterol-d6 hydrobromide

Fenoterol-d6 hydrobromide (Th-1165a-d6) is the deuterium labeled Fenoterol hydrobromide. Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research[1][2].

Name	5-[2-[[1,1,1,2,3,3-hexadeuterio-3-(4-hydroxyphenyl)propan-2-yl]amino]-1-hydroxyethyl]benzene-1,3-diol,hydrobromide
Synonym	More Synonyms

Description	Fenoterol-d6 hydrobromide (Th-1165a-d6) is the deuterium labeled Fenoterol hydrobromide. Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Inflammation/Immunology
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. R C Heel, et al. Fenoterol: a review of its pharmacological properties and therapeutic efficacy in asthma. Drugs. 1978 Jan;15(1):3-32. [3]. Wei Wang, et al. Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells. Biomed Pharmacother. 2016 Dec;84:185-190. [4]. Nada Choucair-Jaafar, et al. Beta2-adrenoceptor agonists alleviate neuropathic allodynia in mice after chronic treatment. Br J Pharmacol. 2009 Dec;158(7):1683-94. [5]. Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8(1):8161.

Molecular Formula	C₁₇H₁₆BrD₆NO₄
Molecular Weight	390.30200
Exact Mass	389.11100
PSA	92.95000
LogP	3.40660

Fenoterol-d6 Hydrobromide

Airum-d6

Partusisten-d6

Berotec-d6

Phenoterol-d6 Hydrobromide

Fenoterol-d6 Bromide

Dosberotec-d6

Th 1165a-d6

Fenoterol-d6 hydrobromide

Use of Fenoterol-d6 hydrobromide

Names

Fenoterol-d6 hydrobromide Biological Activity

Chemical & Physical Properties

Synonyms