1,4-naphthoquinone structure
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Common Name | 1,4-naphthoquinone | ||
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CAS Number | 130-15-4 | Molecular Weight | 158.153 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 297.9±40.0 °C at 760 mmHg | |
Molecular Formula | C10H6O2 | Melting Point | 119-122 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 111.2±24.3 °C | |
Symbol |
GHS06, GHS08, GHS09 |
Signal Word | Danger |
Use of 1,4-naphthoquinone1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity[1]. |
Name | 1,4-naphthoquinone |
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Synonym | More Synonyms |
Description | 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity[1]. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 297.9±40.0 °C at 760 mmHg |
Melting Point | 119-122 °C(lit.) |
Molecular Formula | C10H6O2 |
Molecular Weight | 158.153 |
Flash Point | 111.2±24.3 °C |
Exact Mass | 158.036774 |
PSA | 34.14000 |
LogP | 1.79 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.617 |
Stability | Stable. Incompatible with strong reducing agents, strong oxidizing agents. |
Water Solubility | insoluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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Symbol |
GHS06, GHS08, GHS09 |
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Signal Word | Danger |
Hazard Statements | H301-H315-H319-H330-H334-H335-H400 |
Precautionary Statements | P260-P273-P284-P301 + P310-P305 + P351 + P338-P310 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
Hazard Codes | T+:Verytoxic;N:Dangerous for the environment; |
Risk Phrases | R25;R26;R36/37/38;R43;R50 |
Safety Phrases | S26-S36/37-S45-S61-S38-S36/37/39-S28A-S24 |
RIDADR | UN 2811 6.1/PG 1 |
WGK Germany | 3 |
RTECS | QL7175000 |
Packaging Group | I |
Hazard Class | 6.1 |
HS Code | 29146910 |
Precursor 10 | |
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DownStream 10 | |
HS Code | 2914690090 |
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Summary | 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Photosensitizing properties of compounds related to benzophenone.
Acta Derm. Venereol. 93(1) , 30-2, (2013) Benzophenone is a phototoxic compound with absorption maxima in the ultraviolet A (UVA) and ultraviolet B (UVB) range. Many benzophenone derivatives are known to be photosensitizing. On the other hand... |
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Combined experimental and simulation studies suggest a revised mode of action of the anti-Alzheimer disease drug NQ-Trp.
Chemistry 21 , 12657-66, (2015) Inhibition of the aggregation of the monomeric peptide β-amyloid (Aβ) into oligomers is a widely studied therapeutic approach in Alzheimer's disease (AD). Many small molecules have been reported to wo... |
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Posttranslational Regulation of Human DNA Polymerase ι.
J. Biol. Chem. 290 , 27332-44, (2015) Human DNA polymerases (pols) η and ι are Y-family DNA polymerase paralogs that facilitate translesion synthesis past damaged DNA. Both polη and polι can be monoubiquitinated in vivo. Polη has been sho... |
a-Naphthoquinone |
1,4-Naphthalenedione |
naphthoquinone |
α-Naphthoquinone |
Hydronaphthoquinone |
naphthalene-1,4-dione |
para-naphthoquinone |
1,4-Hydronaphthoquinone |
1,4-Naphthoquinone |
1,4-naphthalene-dione |
MFCD00001676 |
EINECS 204-977-6 |