GRP-60367

Modify Date: 2024-01-09 11:56:13

GRP-60367 Structure
GRP-60367 structure
Common Name GRP-60367
CAS Number 1309241-34-6 Molecular Weight 353.46
Density N/A Boiling Point N/A
Molecular Formula C21H27N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GRP-60367


GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains[1].

 Names

Name GRP-60367

 GRP-60367 Biological Activity

Description GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains[1].
Related Catalog
Target

RABV[1]

In Vitro GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52 nM on different host cell lines[1].
References

[1]. Venice Du Pont, et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor. J Virol. 2020 Jun 16;94(13):e00321-20.

 Chemical & Physical Properties

Molecular Formula C21H27N3O2
Molecular Weight 353.46

 Safety Information

Hazard Codes Xi