10-Vinyl-19-norpregn-4-ene-3,20-dione

Modify Date: 2024-01-08 23:18:25

10-Vinyl-19-norpregn-4-ene-3,20-dione structure	Common Name	10-Vinyl-19-norpregn-4-ene-3,20-dione
	CAS Number	13258-85-0	Molecular Weight	326.47200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₃₀O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 10-Vinyl-19-norpregn-4-ene-3,20-dione

Org OD 02-0 (10-Ethenyl-19-norprogesterone) is a membrane progesterone receptor α (mPRα)-specific agonist (IC50: 33.9 nM). Org OD 02-0 activates MAPK activity. Org OD 02-0 inhibits prolactin (PRL) secretion in the pituitary[1][2].

Name	Org OD 02-0
Synonym	More Synonyms

Description	Org OD 02-0 (10-Ethenyl-19-norprogesterone) is a membrane progesterone receptor α (mPRα)-specific agonist (IC50: 33.9 nM). Org OD 02-0 activates MAPK activity. Org OD 02-0 inhibits prolactin (PRL) secretion in the pituitary[1][2].
Related Catalog	Signaling Pathways >> Others >> Progesterone Receptor Research Areas >> Endocrinology Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK
Target	33.9 nM (mPRα)[1]
References	[1]. Kelder J, et al. Comparison between steroid binding to membrane progesterone receptor alpha (mPRalpha) and to nuclear progesterone receptor: correlation with physicochemical properties assessed by comparative molecular field analysis and identification of mPRalpha-specific agonists. Steroids. 2010 Apr;75(4-5):314-22. [2]. Camilletti MA, et al. Participation of membrane progesterone receptor α in the inhibitory effect of progesterone on prolactin secretion. J Neuroendocrinol. 2018 Sep;30(9):e12614.

Molecular Formula	C₂₂H₃₀O₂
Molecular Weight	326.47200
Exact Mass	326.22500
PSA	34.14000
LogP	4.88960

19-Methylen-progestron

(8S,9S,10S,13S,14S,17S)-17-Acetyl-13-methyl-10-vinyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

10-ethenyl-19-norprogesterone

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 10-Vinyl-19-norpregn-4-ene-3,20-dione
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Use of 10-Vinyl-19-norpregn-4-ene-3,20-dione

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10-Vinyl-19-norpregn-4-ene-3,20-dione Biological Activity

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