3,5-Diiodosalicylic acid

Modify Date: 2024-01-02 12:43:16

3,5-Diiodosalicylic acid Structure
3,5-Diiodosalicylic acid structure
Common Name 3,5-Diiodosalicylic acid
CAS Number 133-91-5 Molecular Weight 389.914
Density 2.7±0.1 g/cm3 Boiling Point 380.8±42.0 °C at 760 mmHg
Molecular Formula C7H4I2O3 Melting Point 220-230 °C (dec.)(lit.)
MSDS USA Flash Point 184.1±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3,5-Diiodosalicylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.7±0.1 g/cm3
Boiling Point 380.8±42.0 °C at 760 mmHg
Melting Point 220-230 °C (dec.)(lit.)
Molecular Formula C7H4I2O3
Molecular Weight 389.914
Flash Point 184.1±27.9 °C
Exact Mass 389.824951
PSA 57.53000
LogP 4.56
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.784
Storage condition -20°C
Water Solubility 0.02 g/100mL (25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VO2800000
CHEMICAL NAME :
Salicylic acid, 3,5-diiodo-
CAS REGISTRY NUMBER :
133-91-5
BEILSTEIN REFERENCE NO. :
2615358
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H4-I2-O3
MOLECULAR WEIGHT :
389.91
WISWESSER LINE NOTATION :
QVR BQ CI EI

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,8,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 19,483,1946

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS VO2800000
HS Code 29182990

 Synthetic Route

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

 Articles26

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Solubilization of human sperm antigens.

Arch. Androl. 15(2-3) , 109-16, (1985)

Various methods of solubilization of human sperm antigens were compared by testing the sperm extracts against rabbit antihuman spermatozoa immune serums with double immunodiffusion and rocket immunoel...

Identification of possible calcium dependent antigens in lithium diiodosalicylate extraction of group A, type 12 streptococcal cell membranes.

Res. Commun. Chem. Pathol. Pharmacol. 49(3) , 401-14, (1985)

Group A, type 12 streptococcal cell membranes were extracted by aqueous lithium diiodosalicylate (LIS) and the extract treated with trifluorotrichloroethane (Genetron). An initial component was isolat...

Antigenic differences in human sperm samples related to various morphological abnormalities.

Arch. Androl. 29(2) , 117-26, (1992)

Sperm samples were collected from male partners of fertile and infertile couples having unexplained and male factor infertility and analyzed for morphological abnormalities. After a staining procedure...

 Synonyms

3,5-diiodosalicyclic acid
3,5-Diiodo-2-hydroxybenzoic acid
Diiodosalicylic acid
EINECS 205-124-0
3,5-Diiodosalicylic acid
RARECHEM AL BE 0656
Sanoform
2-Hydroxy-3,5-diiodobenzoic acid
2-Hydroxy-3,5-dijod-benzoesaeure
Diosal
3,5-DiiodosalicylicAcid
2-hydroxy-3,5-diiodo-benzoic acid
DISA
3,5-diiodo-salicylicaci
5-Diiodosalicylic acid
MFCD00002444
Salicylic acid,3,5-diiodo
Benzoic acid, 2-hydroxy-3,5-diiodo-
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