2,4,6-Triiodophenol

Modify Date: 2024-01-02 19:20:50

2,4,6-Triiodophenol structure	Common Name	2,4,6-Triiodophenol
	CAS Number	609-23-4	Molecular Weight	471.801
	Density	3.1±0.1 g/cm3	Boiling Point	316.3±42.0 °C at 760 mmHg
	Molecular Formula	C₆H₃I₃O	Melting Point	157-159 °C(lit.)
	MSDS	Chinese USA	Flash Point	145.1±27.9 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2,4,6-Triiodophenol

2,4,6-Triiodophenol is an orally active and potent leukotriene B4 (LTB4) synthesis inhibitor. 2,4,6-Triiodophenol can induce mouse blastocysts apoptosis[1][2].

Name	2,4,6-Triiodophenol
Synonym	More Synonyms

Description	2,4,6-Triiodophenol is an orally active and potent leukotriene B4 (LTB4) synthesis inhibitor. 2,4,6-Triiodophenol can induce mouse blastocysts apoptosis[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Others
In Vitro	2,4,6-Triiodophenol (5-50 μM; 0-100 h) impairs the quality of pre-implantation mouse embryos in a dose-dependent manner, inducing decline of both total and trophectoderm cell numbers[2]. 2,4,6-Triiodophenol (5 μM; 85 h) shows increasement of apoptotic cells in mouse pre-implantation embryos[2]. 2,4,6-Triiodophenol (5-50 μM; 100 h) induces oxidative stress in mouse pre-implantation embryos[2]. Apoptosis Analysis[2] Cell Line: Mouse blastocyst cells Concentration: 5 μM Incubation Time: 85 hours Result: Showed signals of activated Caspase-3/7. Immunofluorescence[2] Cell Line: Mouse blastocyst cells Concentration: 5-50 μM Incubation Time: 100 hours Result: Resulted in marked increase of oxygen species (ROS) treated with high dose of 2,4,6-Triiodophenol.

Density	3.1±0.1 g/cm3
Boiling Point	316.3±42.0 °C at 760 mmHg
Melting Point	157-159 °C(lit.)
Molecular Formula	C₆H₃I₃O
Molecular Weight	471.801
Flash Point	145.1±27.9 °C
Exact Mass	471.731781
PSA	20.23000
LogP	3.88
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.816

2,4,6-Triiodophenol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SN2800000

CHEMICAL NAME :: Phenol, 2,4,6-triiodo-

CAS REGISTRY NUMBER :: 609-23-4

BEILSTEIN REFERENCE NO. :: 2046861

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H3-I3-O

MOLECULAR WEIGHT :: 471.79

WISWESSER LINE NOTATION :: QR BI DI FI

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 18,642,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03493

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H312 + H332-H315-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	SN2800000
HS Code	2908199090

Precursor 10
CAS#:108-95-2 Phenol CAS#:98-80-6 Phenylboronic acid CAS#:69-72-7 Salicylic acid CAS#:7553-56-2 molecular iodine
CAS#:554-71-2 4-hydroxy-3,5-d... CAS#:99-96-7 4-Hydroxybenzoi... CAS#:139-02-6 Sodium benzenolate CAS#:119-30-2 5-Iodosalicylic acid
CAS#:618-76-8 Ioxynic acid CAS#:133-91-5 3,5-Diiodosalic...
DownStream 10
CAS#:2012-29-5 2,4-diiodophenol CAS#:88-89-1 Trinitrophenol CAS#:540-38-5 4-Iodophenol CAS#:118-75-2 CHLORANIL
CAS#:87-86-5 Peratox CAS#:305-85-1 2,6-Diiodo-4-ni... CAS#:20294-48-8 2,4-diiodo-6-ni... CAS#:608-71-9 Pentabromophenol
CAS#:20389-01-9 2,6-DIIODO-P-BE... CAS#:20244-55-7 2,4,4,6-Tetrach...

HS Code	2908199090
Summary	HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

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2,6-Triiodophenol

2,4,6-Triiodophenol

Phenol,4,6-triiodo

2,4,6-Trijodfenol

triiodo-2,4,6 phenol

2,3-DIHYDROXYL QUINOXALINE

Phenol, 2,4,6-triiodo-

Phenol,2,4,6-triiodo

EINECS 210-186-7

2,4,6-Trijodfenol [Czech]

2,4,6-triIPhOH

MFCD00002179

2,4,6-triiodo-phenol

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,4,6-Triiodophenol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 2,4,6-Triiodophenol
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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