2,4,6-Triiodophenol
2,4,6-Triiodophenol structure
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Common Name | 2,4,6-Triiodophenol | ||
|---|---|---|---|---|
| CAS Number | 609-23-4 | Molecular Weight | 471.801 | |
| Density | 3.1±0.1 g/cm3 | Boiling Point | 316.3±42.0 °C at 760 mmHg | |
| Molecular Formula | C6H3I3O | Melting Point | 157-159 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 145.1±27.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 2,4,6-Triiodophenol2,4,6-Triiodophenol is an orally active and potent leukotriene B4 (LTB4) synthesis inhibitor. 2,4,6-Triiodophenol can induce mouse blastocysts apoptosis[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2,4,6-Triiodophenol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 2,4,6-Triiodophenol is an orally active and potent leukotriene B4 (LTB4) synthesis inhibitor. 2,4,6-Triiodophenol can induce mouse blastocysts apoptosis[1][2]. |
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| Related Catalog | |
| In Vitro | 2,4,6-Triiodophenol (5-50 μM; 0-100 h) impairs the quality of pre-implantation mouse embryos in a dose-dependent manner, inducing decline of both total and trophectoderm cell numbers[2]. 2,4,6-Triiodophenol (5 μM; 85 h) shows increasement of apoptotic cells in mouse pre-implantation embryos[2]. 2,4,6-Triiodophenol (5-50 μM; 100 h) induces oxidative stress in mouse pre-implantation embryos[2]. Apoptosis Analysis[2] Cell Line: Mouse blastocyst cells Concentration: 5 μM Incubation Time: 85 hours Result: Showed signals of activated Caspase-3/7. Immunofluorescence[2] Cell Line: Mouse blastocyst cells Concentration: 5-50 μM Incubation Time: 100 hours Result: Resulted in marked increase of oxygen species (ROS) treated with high dose of 2,4,6-Triiodophenol. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 3.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 316.3±42.0 °C at 760 mmHg |
| Melting Point | 157-159 °C(lit.) |
| Molecular Formula | C6H3I3O |
| Molecular Weight | 471.801 |
| Flash Point | 145.1±27.9 °C |
| Exact Mass | 471.731781 |
| PSA | 20.23000 |
| LogP | 3.88 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.816 |
| InChIKey | VAPDZNUFNKUROY-UHFFFAOYSA-N |
| SMILES | Oc1c(I)cc(I)cc1I |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H312 + H332-H315-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | SN2800000 |
| HS Code | 2908199090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 10 | |
CAS#:108-95-2
CAS#:98-80-6
CAS#:69-72-7
CAS#:7553-56-2
CAS#:554-71-2
CAS#:99-96-7
CAS#:139-02-6
CAS#:119-30-2
CAS#:618-76-8
CAS#:133-91-5
CAS#:2012-29-5
CAS#:88-89-1
CAS#:540-38-5
CAS#:118-75-2
CAS#:87-86-5
CAS#:305-85-1
CAS#:20294-48-8
CAS#:608-71-9
CAS#:20389-01-9
CAS#:20244-55-7This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2908199090 |
|---|---|
| Summary | HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Distribution of dehalogenation activity in subseafloor sediments of the Nankai Trough subduction zone.
Philos. Trans. R. Soc. Lond., B, Biol. Sci. 368(1616) , 20120249, (2013) Halogenated organic matter buried in marine subsurface sediment may serve as a source of electron acceptors for anaerobic respiration of subseafloor microbes. Detection of a diverse array of reductive... |
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Comparative developmental toxicity of new aromatic halogenated DBPs in a chlorinated saline sewage effluent to the marine polychaete Platynereis dumerilii.
Environ. Sci. Technol. 47(19) , 10868-76, (2013) Using seawater for toilet flushing may introduce high levels of bromide and iodide into a city's sewage treatment works, and result in the formation of brominated and iodinated disinfection byproducts... |
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Fast speciation analysis of iodophenol compounds in river waters by capillary electrophoresis-inductively coupled plasma-mass spectrometry with off-line solid-phase microextraction.
Electrophoresis 25(12) , 1843-51, (2004) An analytical methodology for the fast separation and determination of iodophenol species in natural water samples was developed using capillary electrophoresis (CE) coupled to inductively coupled pla... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2,6-Triiodophenol |
| 2,4,6-Triiodophenol |
| Phenol,4,6-triiodo |
| 2,4,6-Trijodfenol |
| triiodo-2,4,6 phenol |
| 2,3-DIHYDROXYL QUINOXALINE |
| Phenol,2,4,6-triiodo |
| EINECS 210-186-7 |
| 2,4,6-Trijodfenol [Czech] |
| 2,4,6-triIPhOH |
| MFCD00002179 |
| 2,4,6-triiodo-phenol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the melting point of 2,4,6-Triiodophenol? |
| A: Melting point of 2,4,6-Triiodophenol is 157-159 °C(lit.). |
| Q: What is the polar surface area (PSA) of 2,4,6-Triiodophenol? |
| A: Polar surface area (PSA) of 2,4,6-Triiodophenol is 20.23000. |
| Q: What is the InChIKey of 2,4,6-Triiodophenol? |
| A: InChIKey of 2,4,6-Triiodophenol is VAPDZNUFNKUROY-UHFFFAOYSA-N. |
| Q: What are the downstream products of 2,4,6-Triiodophenol? |
| A: Related downstream products(CAS) of 2,4,6-Triiodophenol: 2012-29-5;88-89-1;540-38-5;118-75-2;87-86-5;305-85-1;20294-48-8;608-71-9;20389-01-9;20244-55-7. |
| Q: What is the LogP of 2,4,6-Triiodophenol? |
| A: LogP of 2,4,6-Triiodophenol is 3.88. |
| Q: What is the CAS number of 2,4,6-Triiodophenol? |
| A: CAS number of 2,4,6-Triiodophenol is 609-23-4. |
| Q: What is the English name of 2,4,6-Triiodophenol? |
| A: The English name of 2,4,6-Triiodophenol is 2,4,6-Triiodophenol. |
| Q: What is the molecular weight of 2,4,6-Triiodophenol? |
| A: Molecular weight of 2,4,6-Triiodophenol is 471.801. |
| Q: What are the upstream materials of 2,4,6-Triiodophenol? |
| A: Related upstream materials(CAS) of 2,4,6-Triiodophenol: 108-95-2;98-80-6;69-72-7;7553-56-2;554-71-2;99-96-7;139-02-6;119-30-2;618-76-8;133-91-5. |
| Q: What English synonyms does 2,4,6-Triiodophenol have? |
| A: English synonyms of 2,4,6-Triiodophenol: 2,6-Triiodophenol, 2,4,6-Triiodophenol, Phenol,4,6-triiodo, 2,4,6-Trijodfenol, triiodo-2,4,6 phenol, 2,3-DIHYDROXYL QUINOXALINE, Phenol,2,4,6-triiodo, EINECS 210-186-7, 2,4,6-Trijodfenol [Czech], 2,4,6-triIPhOH, MFCD00002179, 2,4,6-triiodo-phenol. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |