Amino-PEG8-hydrazide-Boc

Modify Date: 2024-01-08 12:28:51

Amino-PEG8-hydrazide-Boc Structure
Amino-PEG8-hydrazide-Boc structure
Common Name Amino-PEG8-hydrazide-Boc
CAS Number 1334169-96-8 Molecular Weight 555.65936
Density N/A Boiling Point N/A
Molecular Formula C24H49N3O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG8-hydrazide-Boc


Amino-PEG8-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG8-t-Boc-Hydrazide
Synonym More Synonyms

 Amino-PEG8-hydrazide-Boc Biological Activity

Description Amino-PEG8-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H49N3O11
Molecular Weight 555.65936

 Synonyms

MFCD21363303
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