Azido-PEG8-hydrazide

Modify Date: 2024-01-15 19:23:13

Azido-PEG8-hydrazide Structure
Azido-PEG8-hydrazide structure
Common Name Azido-PEG8-hydrazide
CAS Number 2353410-11-2 Molecular Weight 481.54
Density N/A Boiling Point N/A
Molecular Formula C19H39N5O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG8-hydrazide


Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG8-hydrazide

 Azido-PEG8-hydrazide Biological Activity

Description Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H39N5O9
Molecular Weight 481.54