Rimantadine

Modify Date: 2024-01-02 08:13:41

Rimantadine structure	Common Name	Rimantadine
	CAS Number	13392-28-4	Molecular Weight	179.30
	Density	1.033	Boiling Point	248ºC
	Molecular Formula	C₁₂H₂₁N	Melting Point	375°C(lit.)
	MSDS	N/A	Flash Point	99ºC

Use of Rimantadine

Rimantadine (Flumadine) is an anti-influenza virus drug.Target: Influenza Virusrimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2].

Name	1-(1-adamantyl)ethanamine
Synonym	More Synonyms

Description	Rimantadine (Flumadine) is an anti-influenza virus drug.Target: Influenza Virusrimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
References	[1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78. [2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82.

Description

Related Catalog

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

References

[1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78.

[2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82.

Density	1.033
Boiling Point	248ºC
Melting Point	375°C(lit.)
Molecular Formula	C₁₂H₂₁N
Molecular Weight	179.30
Flash Point	99ºC
PSA	26.02000
LogP	4.05230
Vapour Pressure	0.0249mmHg at 25°C
Index of Refraction	1.539
Storage condition	-20°C

Rimantadine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU4716000

CHEMICAL NAME :: 1-Adamantanemethylamine, alpha-methyl-

CAS REGISTRY NUMBER :: 13392-28-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H21-N

MOLECULAR WEIGHT :: 179.34

Hazard Codes	Xn
HS Code	2921300090

1-adamantyl met...

CAS#:78679-71-7

~98%

Rimantadine

CAS#:13392-28-4

Literature: E. I. Du Pont de Nemours and Company Patent: US4551552 A1, 1985 ;

1-Acetyladamantane

CAS#:1660-04-4

~85%

Rimantadine

CAS#:13392-28-4

Literature: Vashkevich; Kozlov; Potkin Russian Journal of Organic Chemistry, 1999 , vol. 35, # 12 p. 1773 - 1776

acetyladamantan...

CAS#:1707-40-0

Rimantadine

CAS#:13392-28-4

Literature: Journal of medicinal chemistry, , vol. 14, # 6 p. 535 - 543

Precursor 3
CAS#:78679-71-7 1-adamantyl met... CAS#:1660-04-4 1-Acetyladamantane CAS#:1707-40-0 acetyladamantan...
DownStream 1
CAS#:90812-24-1 3-(1-aminoethyl...

HS Code	2921300090
Summary	2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

1-adamantanemethylamine

tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride

a-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride

Remantadine

Meradan

α-Methyl-1-adamantanemethylamine hydrochloride

UNII:JEI07OOS8Y

[1-(1-Adamantyl)ethyl]amine hydrochloride

Rimant

MFCD03265511

1-tricyclo[3.3.1.1]déc-1-yléthanamine chlorhydrate

1-(Adamantan-1-yl)ethanamine hydrochloride (1:1)

Roflual

Rimantadinum

1-(tricyclo[3.3.1.1]dec-1-yl)ethanamine hydrochloride (1:1)

Tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride (1:1)

Flumadine

a-Methyl-1-adamantanemethylamine Hydrochloride

1-Tricyclo[3.3.1.1]dec-1-ylethanaminhydrochlorid

Rimantadina

Rimantadine

Rimantadine Hydrochloride

1-tricyclo[3.3.1.1]dec-1-ylethanamine hydrochloride

Riamantadine

Remantadine hydrochloride

DC Chemicals Limited
China
Product Name: Rimantadine (Flumadine)
Price: $250.0/100mg $500.0/250mg $1000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Rimantadine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 1-AdaMantanethylaMine
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Rimantadine

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