Dynamin IN-2

Modify Date: 2024-04-10 19:07:51

Dynamin IN-2 structure	Common Name	Dynamin IN-2
	CAS Number	1345853-49-7	Molecular Weight	364.87
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₁ClN₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dynamin IN-2

Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM[1].

Name	Dynamin IN-2

Description	Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Cytoskeleton >> Dynamin
Target	IC50: 1.0 ± 0.2 μM (dyn I GTPase), 9.5 ± 2.5 μM (CME)[1]
References	[1]. Cossar PJ, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.

Molecular Formula	C₂₂H₂₁ClN₂O
Molecular Weight	364.87

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Dynamin IN-2
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.