DYRKs-IN-2

Modify Date: 2025-08-25 13:54:51

DYRKs-IN-2 structure	Common Name	DYRKs-IN-2
	CAS Number	1386980-04-6	Molecular Weight	632.16
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₃₈ClN₉O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DYRKs-IN-2

DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].

Name	DYRKs-IN-2

Description	DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> DYRK
Target	IC50: 30.6 nM (DYRK1B) and 12.8 nM (DYRK1A)[2]
In Vitro	DYRKs-IN-2 (Example 132) has an EC50 of 22.8 nM for SW620 cell line[1].
References	[1]. Kevin Anderson, et al. Pyrido pyrimidines. US20120184542A1

Molecular Formula	C₃₂H₃₈ClN₉O₃
Molecular Weight	632.16

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