8-amino-3,6-dioxaoctanoic acid

Modify Date: 2025-08-26 22:18:02

8-amino-3,6-dioxaoctanoic acid Structure
8-amino-3,6-dioxaoctanoic acid structure
Common Name 8-amino-3,6-dioxaoctanoic acid
CAS Number 134978-97-5 Molecular Weight 163.17
Density 1.2±0.1 g/cm3 Boiling Point 323.8±22.0 °C at 760 mmHg
Molecular Formula C6H13NO4 Melting Point 124.0 to 128.0 °C
MSDS N/A Flash Point 149.6±22.3 °C

 Use of 8-amino-3,6-dioxaoctanoic acid


H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB)[1].

 Names

Name 2-[2-(2-aminoethoxy)ethoxy]acetic acid
Synonym More Synonyms

 8-amino-3,6-dioxaoctanoic acid Biological Activity

Description H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB)[1].
Related Catalog
References

[1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 323.8±22.0 °C at 760 mmHg
Melting Point 124.0 to 128.0 °C
Molecular Formula C6H13NO4
Molecular Weight 163.17
Flash Point 149.6±22.3 °C
Exact Mass 163.084457
PSA 81.78000
LogP -1.59
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.467
Storage condition -20°C

 Safety Information

HS Code 2922509090

 Synthetic Route

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8-amino-3,6-dioxaoctanoic acid Structure

8-amino-3,6-dio...

CAS#:134978-97-5

Literature: Organic Letters, , vol. 7, # 9 p. 1699 - 1702

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8-amino-3,6-dioxaoctanoic acid Structure

8-amino-3,6-dio...

CAS#:134978-97-5

Literature: Organic and Biomolecular Chemistry, , vol. 6, # 17 p. 3065 - 3078

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8-amino-3,6-dioxaoctanoic acid Structure

8-amino-3,6-dio...

CAS#:134978-97-5

Literature: WO2006/82245 A1, ; Page/Page column 357 ;

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Acetic acid,2-[2-(2-aminoethoxy)ethoxy]
(2-aminoethoxy)ethoxyacetic acid
8-Amino-3,6-dioxaoctanoic acid
2-(2-(2-Aminoethoxy)ethoxy)acetic acid
[2-(2-Aminoethoxy)ethoxy]acetic acid
Acetic acid, 2-[2-(2-aminoethoxy)ethoxy]-
[2-(N-2-amino ethoxy)ethoxy] acetic acid
ADOA
AEEA
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