DBCO-NHS ester
Modify Date: 2024-01-12 09:24:05
DBCO-NHS ester structure
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Common Name | DBCO-NHS ester | ||
|---|---|---|---|---|
| CAS Number | 1353016-71-3 | Molecular Weight | 402.39900 | |
| Density | 1.43±0.1 g/cm3 | Boiling Point | 670.2±65.0 °C at 760 mmHg | |
| Molecular Formula | C23H18N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DBCO-NHS esterDBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| Name | Dibenzocyclooctyne-N-hydroxysuccinimidyl ester |
|---|---|
| Synonym | More Synonyms |
| Description | DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.43±0.1 g/cm3 |
|---|---|
| Boiling Point | 670.2±65.0 °C at 760 mmHg |
| Molecular Formula | C23H18N2O5 |
| Molecular Weight | 402.39900 |
| Exact Mass | 402.12200 |
| PSA | 83.99000 |
| LogP | 2.32330 |
| Storage condition | 2-8℃ |
| Hazard Codes | Xi |
|---|
| DBCO-NHS ester |
| Dibenzylcyclooctyne-NHS ester |
| Dibenzocyclooctyne-N-hydroxysuccinimidyl ester |
| DBCO-succinyl N-hydroxysuccinimidyl ester |
| 2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate |
| 2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate |