DBCO-PEG4-NHS ester
Modify Date: 2024-01-09 09:06:18
DBCO-PEG4-NHS ester structure
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Common Name | DBCO-PEG4-NHS ester | ||
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| CAS Number | 1427004-19-0 | Molecular Weight | 649.688 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C34H39N3O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DBCO-PEG4-NHS esterDBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 4-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-N-{15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-4-oxobutanamide |
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| Synonym | More Synonyms |
| Description | DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C34H39N3O10 |
| Molecular Weight | 649.688 |
| Exact Mass | 649.263550 |
| LogP | 0.56 |
| Index of Refraction | 1.608 |
| Storage condition | -20°C |
| Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-γ-oxo- |
| 4-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-N-{15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-4-oxobutanamide |