(D-Arg0,Hyp3,D-Phe7,Leu8)-Bradykinin structure
|
Common Name | (D-Arg0,Hyp3,D-Phe7,Leu8)-Bradykinin | ||
---|---|---|---|---|
CAS Number | 135701-67-6 | Molecular Weight | 1248.436 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C57H89N19O13 | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Name | [D-Arg0,Hyp3,D-Phe7,Leu8]-Bradykinin |
---|---|
Synonym | More Synonyms |
Density | 1.5±0.1 g/cm3 |
---|---|
Molecular Formula | C57H89N19O13 |
Molecular Weight | 1248.436 |
Exact Mass | 1247.688721 |
PSA | 533.80000 |
LogP | -1.49 |
Index of Refraction | 1.681 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
RIDADR | NONH for all modes of transport |
New highly potent bradykinin B2 receptor antagonists.
Agents Actions 34 , 138-141, (1991) pA2 values of new B2 receptor antagonists ranging from 7.51 to 8.86 were measured on the rabbit jugular vein, while lower values were observed in the other preparations (for instance, the hamster urin... |
|
Non-selectivity of new bradykinin antagonists for B1 receptors.
Life Sci. 51 , PL 125, (1992) Two new B1 receptor antagonists, [Hyp3,Thi5,DTic7,Oic8]desArg9-BK and DArg[Hyp3,Thi5,DTic7,Oic8]desArg9-BK were tested in vitro on the rabbit jugular vein and the guinea pig ileum (preparations contai... |
|
A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers.
J. Med. Chem. 35 , 1563, (1992) A systematic study on the dimerization of the bradykinin (BK) antagonist D-Arg0-Arg1-Pro2-Hyp3-Gly4-Phe5-Ser6-D-Phe 7-Leu8-Arg9 has been performed. The first part of this study involved compounds wher... |
D-ARG-ARG-PRO-HYP-GLY-PHE-SER-D-PHE-LEU-ARG |
L-Ornithine, N-(diaminomethylene)-D-ornithyl-N-(diaminomethylene)-L-ornithyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-seryl-D-phenylalanyl-L-leucyl-N-(diaminomethylene)- |
Leu(8)]-bradykinin B2 |
D-Arg-L-Arg-L-Pro-L-t4Hyp-Gly-L-Phe-L-Ser-D-Phe-L-Leu-L-Arg-OH |
D-ARG-[HYP3,D-PHE7,LEU8]-BRADYKININ |
H-D-ARG-ARG-PRO-HYP-GLY-PHE-SER-D-PHE-LEU-ARG-OH |
D-Arg(0)[Hyp(3),D-Phe(7),Leu(8)]-BK |
D-Arg-L-Arg-L-Pro-4-Hydroxy-L-Pro-Gly-L-Phe-L-Ser-D-Phe-L-Leu-L-Arg-OH |
Aaphgpspla |
(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ |
bradykinin,Arg-Hyp(3)-Phe(7)-Leu(8) |
N-(Diaminomethylene)-D-ornithyl-N-(diaminomethylene)-L-ornithyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-seryl-D-phenylalanyl-L-leucyl-N-(diaminomethylene)-L-ornithine |
D-Arg(0)[Hyp(3) |