Thiol-PEG3-phosphonic acid

Modify Date: 2024-01-12 20:35:20

Thiol-PEG3-phosphonic acid Structure
Thiol-PEG3-phosphonic acid structure
Common Name Thiol-PEG3-phosphonic acid
CAS Number 1360716-36-4 Molecular Weight 274.27
Density N/A Boiling Point N/A
Molecular Formula C8H19O6PS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thiol-PEG3-phosphonic acid


Thiol-PEG3-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Thiol-PEG3-phosphonic acid

 Thiol-PEG3-phosphonic acid Biological Activity

Description Thiol-PEG3-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H19O6PS
Molecular Weight 274.27