HJC 0197
Modify Date: 2024-01-09 15:33:06
HJC 0197 structure
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Common Name | HJC 0197 | ||
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| CAS Number | 1383539-73-8 | Molecular Weight | 339.45500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H21N3OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HJC 0197HJC0197 is a potent Epac1 (exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 μM for Epac2) antagonist. HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP[1]. |
| Name | hjc0197 |
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| Synonym | More Synonyms |
| Description | HJC0197 is a potent Epac1 (exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 μM for Epac2) antagonist. HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP[1]. |
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| Related Catalog | |
| In Vitro | HJC0197 (25 μM) also inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP[1] |
| References |
| Molecular Formula | C19H21N3OS |
|---|---|
| Molecular Weight | 339.45500 |
| Exact Mass | 339.14100 |
| PSA | 94.84000 |
| LogP | 4.20828 |
| 4-cyclopentyl-2-(2,5-dimethyl-benzylsulfanyl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile |