PF 4800567 hydrochloride

Modify Date: 2023-01-17 11:44:25

PF 4800567 hydrochloride Structure
PF 4800567 hydrochloride structure
Common Name PF 4800567 hydrochloride
CAS Number 1391052-28-0 Molecular Weight 396.271
Density N/A Boiling Point N/A
Molecular Formula C17H19Cl2N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PF 4800567 hydrochloride


PF-4800567 hydrochloride is a casein kinase 1e (CK1e) selective inhibitor (IC50 = 32 nM) that is 20 fold selective for the CK1e isoform over CK1d. PF-4800567 blockes CK1e-mediated PER3 nuclear translocation, but does not effect the circadian clock in animal studies.

 Names

Name 3-[(3-chlorophenoxy)methyl]-1-tetrahydropyran-4-yl-pyrazolo[3,4-d]pyrimidin-4-amine;hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C17H19Cl2N5O2
Molecular Weight 396.271
Exact Mass 395.091583

 Synonyms

MFCD20926348