STK33-IN-1
Modify Date: 2024-01-29 20:00:57
STK33-IN-1 structure
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Common Name | STK33-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 1404437-49-5 | Molecular Weight | 445.52 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 613.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C24H27N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 324.5±34.3 °C | |
Use of STK33-IN-1STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM[1]. |
| Name | N-[3-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-1-(4-methoxyphenyl)-6-pyrazolo[3,4-d]pyrimidinamine |
|---|---|
| Synonym | More Synonyms |
| Description | STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM[1]. |
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| Related Catalog | |
| Target |
IC50: 7 nM (STK33)[1]. |
| In Vitro | STK33-IN-1 (compound 1) is 2-fold selective for Aurora-B (AurB) versus STK33. STK33-IN-1 (compound 1) has proven unsuccessful in selectively killing KRAS-dependent cancer cell lines[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 613.0±65.0 °C at 760 mmHg |
| Molecular Formula | C24H27N7O2 |
| Molecular Weight | 445.52 |
| Flash Point | 324.5±34.3 °C |
| Exact Mass | 445.222626 |
| LogP | 3.12 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.674 |
| N-[3-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine |
| N-[3-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-1-(4-methoxyphenyl)-6-pyrazolo[3,4-d]pyrimidinamine |
| 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, N-[3-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-1-(4-methoxyphenyl)- |